Description |
cell division cycle 25B |
MAPK activated protein kinase 2 |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Staurosporine
- 3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione
- (4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE
- (10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one
- (3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one
- 2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE
- 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE
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Diseases |
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GWAS |
- Basophil percentage of granulocytes ( 27863252)
- Cognitive decline rate in late mild cognitive impairment ( 26252872)
- Mean corpuscular hemoglobin ( 32888494)
- Mean corpuscular volume ( 32888494)
- Mean reticulocyte volume ( 32888494)
- Mean spheric corpuscular volume ( 32888494)
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Interacting Genes |
28 interacting genes:
AATK
AR
AURKA
BRSK1
BRSK2
CDC14A
CDK1
CDK2
CDK5
CHEK1
CREBBP
CSNK2A1
CSNK2B
ESR1
FHL3
KAT2B
MAPK14
MAPK9
MAPKAPK2
MELK
PGR
PSME3
SFN
YWHAB
YWHAE
YWHAH
YWHAQ
YWHAZ
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42 interacting genes:
AGO2
AKT1
ALOX5
ARPC5
ATF1
BAG2
BCL2L1
BECN1
CDC25B
CEP131
CREB1
DDX5
DES
EEF2K
ETV1
HNRNPA0
HSF1
HSPB1
LIMK1
LSP1
MAP2K6
MAPK14
MAPK3
MDM2
PABPC1
PARN
PHC2
PIAS2
RCSD1
SHC1
SRF
STAT3
TCF3
TH
TRIM28
TRIM29
TSC2
UBE2J1
WASF1
YWHAZ
ZFP36
ZFP36L1
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Entrez ID |
994 |
9261 |
HPRD ID |
00307 |
11882 |
Ensembl ID |
ENSG00000101224
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ENSG00000162889
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Uniprot IDs |
B3KS38
B4DIG0
B4DQZ3
B4DRC3
E1YMX4
G8JLH2
P30305
Q6MZW8
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P49137
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PDB IDs |
1CWR
1CWS
1CWT
1QB0
1YM9
1YMD
1YMK
1YML
1YS0
2A2K
2IFD
2IFV
2UZQ
3FQT
3FQU
4WH7
4WH9
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1KWP
1NXK
1NY3
2JBO
2JBP
2OKR
2ONL
2OZA
2P3G
2PZY
3A2C
3FPM
3FYJ
3FYK
3GOK
3KA0
3KC3
3KGA
3M2W
3M42
3R2B
3R2Y
3R30
3WI6
4TYH
6TCA
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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