DYDC2 and POLR1A

Data Source:
BioGRID (two hybrid)

		DYDC2	POLR1A
Description		DPY30 domain containing 2	RNA polymerase I subunit A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region MLL3/4 Complex Set1C/COMPASS Complex	Nucleoplasm Chromosome RNA Polymerase I Complex
	Molecular Function	Protein Binding	RNA Polymerase I Activity DNA Binding Chromatin Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Zinc Ion Binding
	Biological Process	Chromatin Silencing At Telomere Histone H3-K4 Methylation	Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Positive Regulation Of Gene Expression, Epigenetic Negative Regulation Of Protein Localization To Nucleolus
Pathways			NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31451708) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)	Facial emotion recognition (sad faces) ( 28608620)
Interacting Genes		5 interacting genes: DPY30 NME5 POLR1A TENT5D UBXN2A	10 interacting genes: ANP32B DYDC2 MEOX2 NFKBIB NOLC1 POLR1E PTEN REL RRN3 TCF4
Entrez ID		84332	25885
HPRD ID		11311	10161
Ensembl ID		ENSG00000133665	ENSG00000068654
Uniprot IDs		A0A0A0MRQ7 Q96IM9	O95602
PDB IDs
Enriched GO Terms of Interacting Partners?
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