SPATC1L and PIAS2

Data Source:
BioGRID (two hybrid)

		SPATC1L	PIAS2
Description		spermatogenesis and centriole associated 1 like	protein inhibitor of activated STAT 2
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Centrosome Sperm Connecting Piece	Nucleus Nucleoplasm PML Body Nuclear Speck
	Molecular Function	Molecular_function Protein Binding Protein Kinase A Regulatory Subunit Binding	RNA Polymerase II Transcription Factor Binding DNA Binding Transcription Coregulator Activity Protein Binding Transcription Factor Binding Zinc Ion Binding SUMO Transferase Activity Ubiquitin Protein Ligase Binding SUMO Ligase Activity
	Biological Process	Spermatogenesis Biological_process Actin Polymerization Or Depolymerization Positive Regulation Of Protein Kinase A Signaling Positive Regulation Of CAMP-dependent Protein Kinase Activity	Regulation Of Transcription By RNA Polymerase II Protein Sumoylation Negative Regulation Of Androgen Receptor Signaling Pathway
Pathways			Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS			Fruit consumption ( 32066663)
Interacting Genes		46 interacting genes: ACOT7 ARL4A ARMC7 ATPAF2 CABP2 DISC1 EXOSC8 FOXN1 FSD2 GOLGA6A GTF3C6 HOOK2 IKZF1 KIFC3 KRT40 KRTAP5-9 LZTS2 MISP MTUS2 MYO15B NCK2 NUTF2 NXF1 PARN PHC2 PHF11 PIAS2 PICK1 PNMA1 POLR1C PPP1CB PPP1CC QARS1 RAD51D RBMY1F RBMY1J REL SIAH1 SYCE1 TCF4 TEKT4 TRIM27 TRMO TSR2 UBL5 ZBTB8B	125 interacting genes: ACY3 ADA AKT1 AR ATF2 C1QA C5orf24 CBS CBSL CCHCR1 CCNDBP1 CDCA8 CGGBP1 CHMP4B CLDN2 CREB1 CREBBP CTBP1 DDX39B DES DEUP1 DMC1 DNMT3A EDC3 ELK1 ESR1 ESR2 EXOSC8 FAM118B FKBP6 FLI1 GFAP GLUL GOLGA2 GRHL2 GRM8 GTF2I GTF2IRD1 HDAC3 HMBOX1 HMG20A HMG20B HMGXB4 HNRNPCL1 HNRNPUL1 HOMER1 HOOK1 HUWE1 IKZF1 IMPDH1 JUN KIFC3 LCE1E LCE2C LMNA LMNB1 MAPK8 MAPKAPK2 MBD1 MITF MLX MSX2 MX1 MX2 NAV2 NME7 NR3C1 PAICS PARK7 PAXIP1 PGR PHC1 PIAS1 PIAS4 PLAG1 PLAGL1 PML PRKAB2 PRKRA PRPH RFX2 RUFY1 RUNX1T1 SEC23A SIAH1 SIAH2 SMAD3 SMAD4 SNAI2 SNIP1 SOX5 SPATC1L SPINDOC SREBF2 STAT4 SUMO1 SUMO1P1 SUMO2 SUMO3 SYN3 TH TICAM2 TP53 TRAF2 TRAF3 TRAF5 TRIM23 TRIM27 TRIM50 TRIM55 TRIM63 TSR2 TXLNA UBASH3B UBE2I UBE2L3 UBQLN1 ZBED1 ZBTB16 ZBTB8A ZC3H10 ZFP42 ZNF319 ZNF451 ZNRD2
Entrez ID		84221	9063
HPRD ID		10753	06944
Ensembl ID		ENSG00000160284	ENSG00000078043
Uniprot IDs		Q9H0A9	A0A024RC49 O75928 Q2TA77
PDB IDs			2ASQ 4FO9
Enriched GO Terms of Interacting Partners?
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