STX7 and TMX2

Data Source:
BioGRID (two hybrid)

		STX7	TMX2
Description		syntaxin 7	thioredoxin related transmembrane protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Endocytic Vesicle SNARE Complex Early Endosome Membrane Vesicle Azurophil Granule Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome Tertiary Granule	Mitochondrion Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondrial Membrane Membrane-bounded Organelle Mitochondria-associated Endoplasmic Reticulum Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity Syntaxin Binding	Protein Binding Disulfide Oxidoreductase Activity Identical Protein Binding
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Intracellular Protein Transport Vesicle Fusion Vesicle Docking Organelle Localization Organelle Assembly Positive Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Plasma Membrane	Brain Development
Pathways
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Autism spectrum disorder or schizophrenia ( 28540026) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neuroticism ( 29255261) Problematic alcohol use ( 32451486) Reticulocyte count ( 32888494) Schizophrenia ( 25056061 29483656)
Interacting Genes		54 interacting genes: ANKS6 AQP6 ARL13B CERS4 CISD2 CREB3 CREB3L1 CYBRD1 DNAJC5 EBP ELOVL5 ENTPD2 FAM174A FAM210B FKBP7 GJC3 HSD17B11 HSD17B13 JAGN1 LIME1 LMNA LSMEM2 MAPK6 MFF MGST3 MRM1 MTUS1 NAPA REEP1 RETREG3 RIC3 SAR1A SLC10A1 SLC10A6 SNAP29 STX1A STX2 STX4 STX6 STX8 TM4SF19 TMEM205 TMEM241 TMEM267 TMEM80 TMPRSS2 TMX2 VAMP7 VAMP8 VPS11 VPS16 VPS18 VTI1B ZFYVE27	164 interacting genes: AGPAT3 AGPAT4 AGPAT5 AIG1 AQP6 ARV1 ASGR1 ASPH ATXN1 BDKRB1 BET1 BNIP1 BNIP2 BNIP3 BRICD5 BTN2A2 C2CD2L C3orf52 CCDC167 CCL2 CD81 CDIPT CDS2 CMTM7 COL8A2 COMMD8 COX20 CTSA CTXN3 CXCL16 CXorf66 CYBC1 CYP4F2 DERL1 DGAT2L6 EMD EMP3 F2RL1 FA2H FAM177A1 FAM241B FAM3C FAXDC2 FDFT1 FUNDC2 FXYD6-FXYD2 GIMAP1 GIMAP5 GJB2 HACD2 HHATL HMOX2 HSD17B11 HSD17B13 HSD3B7 HTATIP2 IER3 IER3IP1 IGFBP5 INSIG2 ITGAM LEPROT LEPROTL1 LHFPL5 LRAT MALL MFF MFSD14B MGLL MGST3 MIP MLN MS4A1 MTNR1A NAT8 NDUFA3 NINJ2 NRM NSDHL NSG1 ORMDL2 OTULINL PAEP PEDS1-UBE2V1 PEX16 PKMYT1 PLP2 PNLIPRP1 PRAF2 PRB1 PTAFR PTPN9 RABAC1 REEP2 REEP4 RFT1 RNF24 RTP2 RUSF1 SACM1L SCAMP5 SCD SELENOK SERF1A SERF1B SERP2 SFT2D1 SFXN1 SFXN3 SLC22A18 SLC22A2 SLC29A2 SLC35A1 SMAGP SMCO4 SMIM1 STATH STX12 STX3 STX7 THBD THSD7B TMBIM6 TMEM115 TMEM120A TMEM120B TMEM121 TMEM128 TMEM140 TMEM14B TMEM14C TMEM176A TMEM201 TMEM203 TMEM208 TMEM222 TMEM239 TMEM254 TMEM31 TMEM50B TMEM51 TMEM65 TMEM71 TMEM86B TMEM97 TPRG1 TRAM1L1 TREX1 TSNARE1 TSPAN2 TVP23B UBE2J1 UNC93A VAMP1 VAMP3 VAMP4 VAMP5 VAPA VAPB WFDC2 YIF1A YIPF1 YIPF2 YIPF6
Entrez ID		8417	51075
HPRD ID		04449	07159
Ensembl ID		ENSG00000079950	ENSG00000213593
Uniprot IDs		O15400	Q9Y320
PDB IDs			2DJ0
Enriched GO Terms of Interacting Partners?
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