EPHB6 and HDHD2

Data Source:
HPRD (two hybrid)

		EPHB6	HDHD2
Description		EPH receptor B6	haloacid dehalogenase like hydrolase domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection Receptor Complex	Extracellular Exosome
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activity Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity ATP Binding Signaling Receptor Activity	Protein Binding Phosphatase Activity Enzyme Binding Metal Ion Binding
	Biological Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Axon Guidance Peptidyl-tyrosine Phosphorylation Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Kinase Activity Ephrin Receptor Signaling Pathway	Biological_process Dephosphorylation
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells
Drugs		Fostamatinib
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576 29875488) Cancer ( 29299148)	Blood protein levels ( 30072576 29875488) Fruit consumption ( 32066663)
Interacting Genes		27 interacting genes: AFDN ASB12 CBL CRK CRKL DDIT4L DUSP18 DUSP19 EFNB2 EPHB1 ERBB2 GRB2 HDHD2 INCA1 MSX2 MTARC1 NIF3L1 NOTCH2NLA POU6F2 PRMT5 REL SAT1 STYX TCF4 TEKT5 TRIB3 TRIM39	12 interacting genes: ADGRB2 CFD CRMP1 DVL1 EPHB6 LUC7L2 MEOX2 MGST2 PIP5K1C SOD2 TARBP2 TRAPPC11
Entrez ID		2051	84064
HPRD ID		04133	13640
Ensembl ID		ENSG00000106123	ENSG00000167220
Uniprot IDs		F8WCM8 J3KQU5 O15197	Q9H0R4 V9HW73
PDB IDs			3HLT
Enriched GO Terms of Interacting Partners?
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