SLC25A11 and C5AR2

Data Source:
BioGRID (two hybrid)

		SLC25A11	C5AR2
Description		solute carrier family 25 member 11	complement component 5a receptor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Integral Component Of Plasma Membrane	Plasma Membrane Basal Plasma Membrane Integral Component Of Membrane Apical Part Of Cell
	Molecular Function	RNA Binding Protein Binding Sulfate Transmembrane Transporter Activity Thiosulfate Transmembrane Transporter Activity Oxaloacetate Transmembrane Transporter Activity Malate Transmembrane Transporter Activity Succinate Transmembrane Transporter Activity Antiporter Activity Oxoglutarate:malate Antiporter Activity	Complement Receptor Activity Complement Component C5a Receptor Activity G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Gluconeogenesis Sulfate Transport Thiosulfate Transport Oxaloacetate Transport Alpha-ketoglutarate Transport Phosphate Ion Transmembrane Transport Succinate Transmembrane Transport Malate Transmembrane Transport Oxaloacetate(2-) Transmembrane Transport Sulfate Transmembrane Transport	Complement Receptor Mediated Signaling Pathway Chemotaxis Inflammatory Response Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Complement Activation Regulation Of Interleukin-8 Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Complement Component C5a Signaling Pathway Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Neutrophil Chemotaxis
Pathways		Gluconeogenesis	Peptide ligand-binding receptors Regulation of Complement cascade
Drugs
Diseases
GWAS		Platelet count ( 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 27863252)
Interacting Genes		4 interacting genes: C5AR2 CDKN1A COPA SLC22A1	17 interacting genes: ABCA7 ACO2 C3 C4A C4orf3 C5AR1 CALM3 HAGHL HERC2 HERPUD1 PLXDC1 SCN1B SCRIB SLC25A11 SLC26A11 SYNGR2 TMEM234
Entrez ID		8402	27202
HPRD ID		05003	17072
Ensembl ID		ENSG00000108528	ENSG00000134830
Uniprot IDs		Q02978 Q6IBH0	Q9P296
PDB IDs
Enriched GO Terms of Interacting Partners?
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