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C5AR2 and PLXDC1
Data Source:
BioGRID
(two hybrid)
C5AR2
PLXDC1
Description
complement component 5a receptor 2
plexin domain containing 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Basal Plasma Membrane
Integral Component Of Membrane
Apical Part Of Cell
Extracellular Region
Cytoplasm
Plasma Membrane
Bicellular Tight Junction
Integral Component Of Membrane
Dendrite
Neuronal Cell Body
Receptor Complex
Molecular Function
Complement Receptor Activity
Complement Component C5a Receptor Activity
G Protein-coupled Receptor Activity
Protein Binding
Protein Binding
Biological Process
Complement Receptor Mediated Signaling Pathway
Chemotaxis
Inflammatory Response
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Regulation Of Complement Activation
Regulation Of Interleukin-8 Production
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Tumor Necrosis Factor Production
Complement Component C5a Signaling Pathway
Positive Regulation Of Epithelial Cell Proliferation
Positive Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Neutrophil Chemotaxis
Angiogenesis
Spinal Cord Development
Pathways
Peptide ligand-binding receptors
Regulation of Complement cascade
Drugs
Diseases
GWAS
Asthma (
31619474
)
Interacting Genes
17 interacting genes:
ABCA7
ACO2
C3
C4A
C4orf3
C5AR1
CALM3
HAGHL
HERC2
HERPUD1
PLXDC1
SCN1B
SCRIB
SLC25A11
SLC26A11
SYNGR2
TMEM234
4 interacting genes:
C5AR2
GPR35
NID1
NRF1
Entrez ID
27202
57125
HPRD ID
17072
08439
Ensembl ID
ENSG00000134830
ENSG00000161381
Uniprot IDs
Q9P296
Q8IUK5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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