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C5AR2

Description complement component 5a receptor 2
Image No pdb structure
GO Annotations Cellular Component
  • Plasma Membrane
  • Basal Plasma Membrane
  • Integral Component Of Membrane
  • Apical Part Of Cell
Molecular Function
  • Complement Receptor Activity
  • Complement Component C5a Receptor Activity
  • G Protein-coupled Receptor Activity
  • Protein Binding
Biological Process
  • Complement Receptor Mediated Signaling Pathway
  • Chemotaxis
  • Inflammatory Response
  • Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
  • Positive Regulation Of Cytosolic Calcium Ion Concentration
  • Regulation Of Complement Activation
  • Regulation Of Interleukin-8 Production
  • Negative Regulation Of Interleukin-6 Production
  • Negative Regulation Of Tumor Necrosis Factor Production
  • Complement Component C5a Signaling Pathway
  • Positive Regulation Of Epithelial Cell Proliferation
  • Positive Regulation Of ERK1 And ERK2 Cascade
  • Negative Regulation Of Neutrophil Chemotaxis
Pathways
  • Peptide ligand-binding receptors
  • Regulation of Complement cascade
Drugs
Diseases
GWAS
Interacting Genes 17 interacting genes: ABCA7 ACO2 C3 C4A C4orf3 C5AR1 CALM3 HAGHL HERC2 HERPUD1 PLXDC1 SCN1B SCRIB SLC25A11 SLC26A11 SYNGR2 TMEM234
Entrez ID 27202
HPRD ID 17072
Ensembl ID ENSG00000134830
Uniprot IDs Q9P296
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025