C5AR2 and SLC26A11

Data Source:
BioGRID (two hybrid)

		C5AR2	SLC26A11
Description		complement component 5a receptor 2	solute carrier family 26 member 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Basal Plasma Membrane Integral Component Of Membrane Apical Part Of Cell	Nucleoplasm Lysosomal Membrane Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Complement Receptor Activity Complement Component C5a Receptor Activity G Protein-coupled Receptor Activity Protein Binding	Protein Binding Secondary Active Sulfate Transmembrane Transporter Activity Anion Transmembrane Transporter Activity Sulfate Transmembrane Transporter Activity Anion:anion Antiporter Activity
	Biological Process	Complement Receptor Mediated Signaling Pathway Chemotaxis Inflammatory Response Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Complement Activation Regulation Of Interleukin-8 Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Complement Component C5a Signaling Pathway Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Neutrophil Chemotaxis	Ion Transport Sulfate Transport Sulfate Transmembrane Transport
Pathways		Peptide ligand-binding receptors Regulation of Complement cascade	Multifunctional anion exchangers
Drugs
Diseases
GWAS			Interleukin-1-receptor antagonist levels ( 22205395) Ischemic stroke ( 26732560)
Interacting Genes		17 interacting genes: ABCA7 ACO2 C3 C4A C4orf3 C5AR1 CALM3 HAGHL HERC2 HERPUD1 PLXDC1 SCN1B SCRIB SLC25A11 SLC26A11 SYNGR2 TMEM234	2 interacting genes: C5AR2 SMIM1
Entrez ID		27202	284129
HPRD ID		17072	11569
Ensembl ID		ENSG00000134830	ENSG00000181045
Uniprot IDs		Q9P296	Q86WA9
PDB IDs
Enriched GO Terms of Interacting Partners?
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