SLC25A11 and SLC22A1

Data Source:
BioGRID (protein complementation assay)

		SLC25A11	SLC22A1
Description		solute carrier family 25 member 11	solute carrier family 22 member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Integral Component Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Presynapse
	Molecular Function	RNA Binding Protein Binding Sulfate Transmembrane Transporter Activity Thiosulfate Transmembrane Transporter Activity Oxaloacetate Transmembrane Transporter Activity Malate Transmembrane Transporter Activity Succinate Transmembrane Transporter Activity Antiporter Activity Oxoglutarate:malate Antiporter Activity	Acetylcholine Transmembrane Transporter Activity Neurotransmitter Transmembrane Transporter Activity Dopamine:sodium Symporter Activity Norepinephrine:sodium Symporter Activity Protein Binding Monoamine Transmembrane Transporter Activity Secondary Active Organic Cation Transmembrane Transporter Activity Organic Cation Transmembrane Transporter Activity Pyrimidine Nucleoside Transmembrane Transporter Activity Quaternary Ammonium Group Transmembrane Transporter Activity Toxin Transmembrane Transporter Activity Identical Protein Binding Xenobiotic Transmembrane Transporter Activity
	Biological Process	Gluconeogenesis Sulfate Transport Thiosulfate Transport Oxaloacetate Transport Alpha-ketoglutarate Transport Phosphate Ion Transmembrane Transport Succinate Transmembrane Transport Malate Transmembrane Transport Oxaloacetate(2-) Transmembrane Transport Sulfate Transmembrane Transport	Neurotransmitter Transport Drug Transmembrane Transport Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Organic Cation Transport Quaternary Ammonium Group Transport Norepinephrine Transport Xenobiotic Transport Epinephrine Transport Serotonin Uptake Norepinephrine Uptake Pyrimidine-containing Compound Transmembrane Transport Dopamine Uptake Cation Transmembrane Transport Transport Across Blood-brain Barrier Acetate Ester Transport Toxin Transport Xenobiotic Transport Across Blood-brain Barrier
Pathways		Gluconeogenesis	Neurotransmitter clearance Norepinephrine Neurotransmitter Release Cycle Abacavir transmembrane transport Na+/Cl- dependent neurotransmitter transporters Organic cation transport
Drugs
Diseases
GWAS		Platelet count ( 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 27863252)	Apolipoprotein B levels ( 32203549) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Blood protein levels ( 28240269) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Essential hypertension (time to event) ( 32589924) Gout ( 22179738) HOMA-B (corrected for HOMA-IR) ( 30369944) LDL cholesterol levels ( 32203549) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Lipoprotein (a) levels ( 26377243) Medication use (HMG CoA reductase inhibitors) ( 31015401) Metabolic traits ( 21886157) Prostate cancer ( 26034056 21743057) Serum metabolite levels ( 23093944) Triglyceride levels ( 32203549) Urinary metabolite levels in chronic kidney disease ( 29545352 31959995)
Interacting Genes		4 interacting genes: C5AR2 CDKN1A COPA SLC22A1	27 interacting genes: ALDOA CAPN1 CCL2 CD63 CD9 CERS2 CHST12 CLPTM1 CYSTM1 FIS1 FXYD2 GHITM KRTCAP2 LAPTM4A LAPTM4B MUC1 PDZK1IP1 POU2AF1 SERP1 SLC25A11 SMIM24 SMIM3 SPP1 TMBIM4 TMEM147 TMEM179B VAPB
Entrez ID		8402	6580
HPRD ID		05003	04007
Ensembl ID		ENSG00000108528	ENSG00000175003
Uniprot IDs		Q02978 Q6IBH0	O15245
PDB IDs
Enriched GO Terms of Interacting Partners?
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