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INO80B and TRIB3
Data Source:
BioGRID
(two hybrid)
INO80B
TRIB3
Description
INO80 complex subunit B
tribbles pseudokinase 3
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Nucleolus
Ino80 Complex
Nucleus
Nucleoplasm
Cytosol
Plasma Membrane
Molecular Function
Protein Binding
Metal Ion Binding
Transcription Corepressor Activity
Protein Kinase Inhibitor Activity
Protein Binding
ATP Binding
Kinase Activity
Protein Kinase Binding
Mitogen-activated Protein Kinase Kinase Binding
Ubiquitin Protein Ligase Binding
Ubiquitin-protein Transferase Regulator Activity
Biological Process
DNA Repair
DNA Recombination
Protein Deubiquitination
ATP-dependent Chromatin Remodeling
Negative Regulation Of Transcription By RNA Polymerase II
Protein Phosphorylation
Negative Regulation Of Protein Kinase Activity
Regulation Of Autophagy
Regulation Of Glucose Transmembrane Transport
Regulation Of Lipid Metabolic Process
Positive Regulation Of Protein Binding
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Insulin Stimulus
Response To Endoplasmic Reticulum Stress
Regulation Of MAP Kinase Activity
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of Fatty Acid Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Ubiquitin-protein Transferase Activity
Negative Regulation Of Protein Kinase B Signaling
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Pathways
UCH proteinases
DNA Damage Recognition in GG-NER
PIP3 activates AKT signaling
Activation of AKT2
PPARA activates gene expression
Negative regulation of the PI3K/AKT network
CD28 dependent PI3K/Akt signaling
VEGFR2 mediated vascular permeability
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Drugs
Diseases
GWAS
Information processing speed (
21130836
)
Logical memory (delayed recall) (
29274321
)
Logical memory (immediate recall) (
29274321
)
Interacting Genes
64 interacting genes:
ABI2
BANP
BHLHB9
BOLL
CARD9
CAVIN1
CCDC85B
CD81
CDR2L
CEP70
CSNK2B
CYSRT1
DPPA4
DVL3
E2F6
FLACC1
GOLGA6L9
HMBOX1
HMGXB4
HOMEZ
HOXA1
HSF2BP
IGFBP2
KCTD7
KRT34
KRT40
KRTAP10-8
KRTAP12-2
KRTAP19-1
KRTAP6-2
LHX4
LIMS1
LZTS2
MID2
MKRN3
MORN3
MTUS2
MYLIP
NBPF19
NOTCH2NLA
PICK1
PIP4K2B
PLAGL2
PNMA1
PNMA2
RBM39
RIMBP3C
SOX13
SSX2IP
STAC3
THAP1
TLE5
TNS2
TRAF2
TRIB3
TRIM27
TSPYL2
U2AF2
UIMC1
USH1G
YAF2
ZNF526
ZNF552
ZRANB1
99 interacting genes:
AKAP8L
AKT1
AKT2
APOBEC3A
APOBEC3C
APP
ARMC7
ATF4
BAG3
BCL6
BFSP2
BMPR2
C21orf58
C22orf39
CBX8
CHAF1A
CLCNKA
COPS6
CTAG1A
CTAG1B
DDIT3
DPPA3
DTX2
EEF1G
EFEMP2
EPHB6
EXOSC5
FAAP20
FAM161A
FAM90A1
FBXO7
GDF9
GIT1
GLIS3
GPATCH2L
GRB2
HAT1
HDAC4
HLA-B
HNRNPF
HOXB5
HOXC8
IL16
INCA1
INO80B
IRX6
KANK2
KAT5
KLHL38
KRT26
LENG1
LMO2
LMO3
MDFI
MISP
OIP5
OSTF1
PADI4
PARD6B
PCSK5
PITX2
PKNOX2
PML
PPP1R26
PPP1R32
PRKAB2
PRMT5
PRR19
PSMA3
RARA
RBM4
RBM48
RELA
RIDA
RPGRIP1
RPSA
SAMD11
SAXO1
SCNM1
SETDB1
SHFL
SNRPC
SPAG8
SPG21
SQSTM1
SUOX
TCF19
TEKT3
TEKT4
TLE5
TRIM55
TRIM63
TTC23
TWIST1
UBTD2
USP20
UTP23
ZNF417
ZNF587
Entrez ID
83444
57761
HPRD ID
17110
09836
Ensembl ID
ENSG00000115274
ENSG00000101255
Uniprot IDs
Q9C086
B4DMM9
J3KR25
Q96RU7
PDB IDs
6HTS
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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