INO80B and IGFBP2

Data Source:
BioGRID (pull down, affinity chromatography technology)

		INO80B	IGFBP2
Description		INO80 complex subunit B	insulin like growth factor binding protein 2
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Ino80 Complex	Extracellular Region Extracellular Space Apical Plasma Membrane Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Protein Binding Metal Ion Binding	Signaling Receptor Binding Protein Binding Insulin-like Growth Factor I Binding Insulin-like Growth Factor II Binding
	Biological Process	DNA Repair DNA Recombination Protein Deubiquitination ATP-dependent Chromatin Remodeling	Signal Transduction Female Pregnancy Aging Response To Nutrient Response To Mechanical Stimulus Response To Lithium Ion Response To Estradiol Response To Retinoic Acid Cellular Response To Hormone Stimulus Regulation Of Growth Positive Regulation Of Activated T Cell Proliferation Response To Drug Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Response To Estrogen Cellular Protein Metabolic Process Response To Glucocorticoid Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		UCH proteinases DNA Damage Recognition in GG-NER	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Drugs
Diseases
GWAS			Glomerular filtration rate (creatinine) ( 28452372) Gut microbiota alpha diversity (Chao1 index) ( 33208821) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Gut microbiota relative abundance (unclassified genus belonging to family Ruminococcaceae) ( 33208821) Mitral valve prolapse ( 26301497) Thyroid stimulating hormone levels ( 25743335) Type 2 diabetes ( 26818947)
Interacting Genes		64 interacting genes: ABI2 BANP BHLHB9 BOLL CARD9 CAVIN1 CCDC85B CD81 CDR2L CEP70 CSNK2B CYSRT1 DPPA4 DVL3 E2F6 FLACC1 GOLGA6L9 HMBOX1 HMGXB4 HOMEZ HOXA1 HSF2BP IGFBP2 KCTD7 KRT34 KRT40 KRTAP10-8 KRTAP12-2 KRTAP19-1 KRTAP6-2 LHX4 LIMS1 LZTS2 MID2 MKRN3 MORN3 MTUS2 MYLIP NBPF19 NOTCH2NLA PICK1 PIP4K2B PLAGL2 PNMA1 PNMA2 RBM39 RIMBP3C SOX13 SSX2IP STAC3 THAP1 TLE5 TNS2 TRAF2 TRIB3 TRIM27 TSPYL2 U2AF2 UIMC1 USH1G YAF2 ZNF526 ZNF552 ZRANB1	6 interacting genes: GSDMB IGF1 IGF2 INO80B KLK2 TF
Entrez ID		83444	3485
HPRD ID		17110	00898
Ensembl ID		ENSG00000115274	ENSG00000115457
Uniprot IDs		Q9C086	C9JMY1 P18065
PDB IDs		6HTS	2H7T
Enriched GO Terms of Interacting Partners?
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