EP400 and TRRAP

Data Source:
HPRD (in vivo, in vitro)

		EP400	TRRAP
Description		E1A binding protein p400	transformation/transcription domain associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Swr1 Complex Nucleoplasm Nuclear Speck NuA4 Histone Acetyltransferase Complex	SAGA Complex PCAF Complex Swr1 Complex Nucleus Nucleoplasm Golgi Apparatus STAGA Complex Transcription Factor TFTC Complex NuA4 Histone Acetyltransferase Complex
	Molecular Function	DNA Binding Chromatin Binding Helicase Activity Protein Binding ATP Binding Protein Antigen Binding	Transcription Coregulator Activity Protein Binding Kinase Activity
	Biological Process	Histone H4 Acetylation Histone H2A Acetylation	DNA Repair Regulation Of Transcription, DNA-templated Phosphorylation Histone Acetylation Histone Deubiquitination Protein Deubiquitination Histone H4 Acetylation Histone H2A Acetylation Beta-catenin-TCF Complex Assembly
Pathways		Formation of Senescence-Associated Heterochromatin Foci (SAHF) DNA Damage/Telomere Stress Induced Senescence HATs acetylate histones	Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex HATs acetylate histones Ub-specific processing proteases
Drugs
Diseases
GWAS		Body mass index ( 26426971) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)	Hemoglobin levels ( 32327693) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		13 interacting genes: ALAS1 BRD8 KAT5 MNS1 MYC NTAQ1 POLR1C RAD51 SUMO2 TBC1D4 TRAF2 TRRAP ZGPAT	18 interacting genes: ACTL6A ATXN7 AURKA BRCA1 BRD8 CDC42 CTNNB1 E2F1 E2F4 EP400 ESR1 KAT2A MAX MRGBP MYC PYGO2 SKP1 TCF3
Entrez ID		57634	8295
HPRD ID		09378	04310
Ensembl ID		ENSG00000183495	ENSG00000196367
Uniprot IDs		Q96L91	Q9Y4A5
PDB IDs
Enriched GO Terms of Interacting Partners?
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