EP400 and BRD8

Data Source:
BioGRID (affinity chromatography technology, two hybrid, affinity chromatography technology)

		EP400	BRD8
Description		E1A binding protein p400	bromodomain containing 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Swr1 Complex Nucleoplasm Nuclear Speck NuA4 Histone Acetyltransferase Complex	Swr1 Complex Nucleoplasm Mitochondrion NuA4 Histone Acetyltransferase Complex
	Molecular Function	DNA Binding Chromatin Binding Helicase Activity Protein Binding ATP Binding Protein Antigen Binding	Protein Binding Nuclear Receptor Coactivator Activity Thyroid Hormone Receptor Binding
	Biological Process	Histone H4 Acetylation Histone H2A Acetylation	Cell Surface Receptor Signaling Pathway Histone Acetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Thyroid Hormone Stimulus
Pathways		Formation of Senescence-Associated Heterochromatin Foci (SAHF) DNA Damage/Telomere Stress Induced Senescence HATs acetylate histones	HATs acetylate histones
Drugs
Diseases
GWAS		Body mass index ( 26426971) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)	Autism spectrum disorder or schizophrenia ( 28540026) Menarche (age at onset) ( 25231870)
Interacting Genes		13 interacting genes: ALAS1 BRD8 KAT5 MNS1 MYC NTAQ1 POLR1C RAD51 SUMO2 TBC1D4 TRAF2 TRRAP ZGPAT	12 interacting genes: AGTR1 EP400 FSD2 MCRS1 MIS18A MRGBP PIN1 PPARG RXRA THRB TRRAP WEE1
Entrez ID		57634	10902
HPRD ID		09378	04166
Ensembl ID		ENSG00000183495	ENSG00000112983
Uniprot IDs		Q96L91	B4DEG9 B4DMS9 B4DN43 Q9H0E9
PDB IDs
Enriched GO Terms of Interacting Partners?
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