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LZTR1 and WWP1
Data Source:
BioGRID
(two hybrid)
LZTR1
WWP1
Description
leucine zipper like transcription regulator 1
WW domain containing E3 ubiquitin protein ligase 1
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Apparatus
Endomembrane System
Cul3-RING Ubiquitin Ligase Complex
Recycling Endosome Membrane
Ubiquitin Ligase Complex
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Extracellular Exosome
Molecular Function
Protein Binding
Small GTPase Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Ubiquitin Protein Ligase Activity
Biological Process
Protein Ubiquitination
Negative Regulation Of Ras Protein Signal Transduction
Protein Polyubiquitination
Signal Transduction
Central Nervous System Development
Protein Ubiquitination
Ion Transmembrane Transport
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Protein Catabolic Process
Negative Regulation Of Transcription, DNA-templated
Viral Entry Into Host Cell
Pathways
Downregulation of ERBB4 signaling
Stimuli-sensing channels
Regulation of RUNX2 expression and activity
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Estimated glomerular filtration rate (
31152163
)
Interacting Genes
55 interacting genes:
AATF
ANKRD53
ASB12
BMPR1B
CEBPZ
CHAF1A
CNOT6L
E2F8
EHMT1
FANK1
GABARAPL2
HCLS1
HDAC4
HRAS
IKBKG
KDM2B
KRAS
L3MBTL3
MCM3
MED16
MED7
MYBL2
NR1H3
NRAS
PAPOLG
PARP1
POLR1B
POLR2B
POLR2E
RAI1
RERE
RIT1
RUVBL1
SCMH1
SND1
SP100
SREBF2
SSX4
STAT1
SUGP2
TAF11
TBX2
TCF19
TFAP2B
TRIM5
TUBGCP4
WWP1
ZBTB1
ZNF137P
ZNF175
ZNF451
ZNF490
ZNF584
ZNF714
ZZZ3
55 interacting genes:
ARRDC1
ARRDC2
ARRDC3
ASH2L
ATN1
CLCN5
CPSF6
DAG1
DAZAP2
DIDO1
EWSR1
FAM189A2
FBXL18
HSPB1
IKBKG
IL2RG
IL6R
KLF2
KLF5
LAPTM5
LATS1
LNX1
LZTR1
MACROH2A2
MIR19A
MIR19B1
NFE2
NOTCH1
PCBD1
PHF20L1
PRKAA2
PYGM
RASA1
RNF11
RTN4
RUNX1
SCNN1A
SFTPC
SMAD3
SMAD5
STAT6
TFAP2A
TGIF1
TP53BP2
TRAF4
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2L3
WASL
WBP1
WBP2
YWHAQ
ZNF638
Entrez ID
8216
11059
HPRD ID
08992
03811
Ensembl ID
ENSG00000099949
ENSG00000123124
Uniprot IDs
A0A384NL67
Q8N653
Q9H0M0
PDB IDs
1ND7
2OP7
5HPS
5HPT
6J1X
6J1Y
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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