MED25 and ODAM

Data Source:
BioGRID (two hybrid)

		MED25	ODAM
Description		mediator complex subunit 25	odontogenic, ameloblast associated
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Transcription Regulator Complex Mediator Complex	Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Cell Periphery Mitotic Spindle Supramolecular Fiber
	Molecular Function	Transcription Coactivator Binding Protein Binding Transcription Factor Binding Retinoic Acid Receptor Binding Retinoid X Receptor Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Chromatin Binding Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Mediator Complex Assembly	Positive Regulation Of Protein Phosphorylation Inflammatory Response Positive Regulation Of Gene Expression Biomineral Tissue Development Regulation Of Actin Cytoskeleton Organization Odontogenesis Of Dentin-containing Tooth Positive Regulation Of GTPase Activity Cellular Protein Metabolic Process Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Amyloid fiber formation
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Blood trace element (Se levels) ( 23720494)
Interacting Genes		37 interacting genes: CDK8 CREBBP CTDP1 CYSRT1 ESRP1 EYA2 FAM168B HCFC1 HGS KLHL12 KRTAP6-1 KRTAP6-3 LASP1 MED1 MED15 MED6 MED8 MED9 NCKIPSD NR3C1 ODAM OXER1 PEF1 PLEKHB2 RARA RORB RUSC1 RXRA SERTAD3 SREBF1 STAT5B TFG THRA TLE5 USP54 WWOX WWP2	13 interacting genes: ADAM15 APP ARID5A HGS IKBKG MED25 POGZ SDCBP SNRPC SPATA31A7 TOLLIP VENTX YPEL3
Entrez ID		81857	54959
HPRD ID		14380	13376
Ensembl ID		ENSG00000104973	ENSG00000109205
Uniprot IDs		Q71SY5	A1E959
PDB IDs		2KY6 2L23 2L6U 2XNF
Enriched GO Terms of Interacting Partners?
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