MED25 and MED15

Data Source:
HPRD (in vivo)

		MED25	MED15
Description		mediator complex subunit 25	mediator complex subunit 15
Image
GO Annotations	Cellular Component	Nucleoplasm Transcription Regulator Complex Mediator Complex	Nucleoplasm Cytoplasm Membrane Mediator Complex
	Molecular Function	Transcription Coactivator Binding Protein Binding Transcription Factor Binding Retinoic Acid Receptor Binding Retinoid X Receptor Binding	Transcription Coregulator Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Chromatin Binding Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Mediator Complex Assembly	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Blood trace element (Se levels) ( 23720494)	Lung function (FEV1/FVC) ( 30061609)
Interacting Genes		37 interacting genes: CDK8 CREBBP CTDP1 CYSRT1 ESRP1 EYA2 FAM168B HCFC1 HGS KLHL12 KRTAP6-1 KRTAP6-3 LASP1 MED1 MED15 MED6 MED8 MED9 NCKIPSD NR3C1 ODAM OXER1 PEF1 PLEKHB2 RARA RORB RUSC1 RXRA SERTAD3 SREBF1 STAT5B TFG THRA TLE5 USP54 WWOX WWP2	12 interacting genes: ATP5F1C ATXN1 CTDP1 FHL3 MED25 MLLT6 PLSCR1 RELA SMAD2 SMAD3 TRIM11 UBC
Entrez ID		81857	51586
HPRD ID		14380	12117
Ensembl ID		ENSG00000104973	ENSG00000099917
Uniprot IDs		Q71SY5	B7Z2H7 G3V1P5 Q6PKB8 Q96RN5
PDB IDs		2KY6 2L23 2L6U 2XNF	2GUT
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?