ODAM and MED25

Data Source:
BioGRID (two hybrid)

		ODAM	MED25
Description		odontogenic, ameloblast associated	mediator complex subunit 25
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Cell Periphery Mitotic Spindle Supramolecular Fiber	Nucleoplasm Transcription Regulator Complex Mediator Complex
	Molecular Function	Protein Binding	Transcription Coactivator Binding Protein Binding Transcription Factor Binding Retinoic Acid Receptor Binding Retinoid X Receptor Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Inflammatory Response Positive Regulation Of Gene Expression Biomineral Tissue Development Regulation Of Actin Cytoskeleton Organization Odontogenesis Of Dentin-containing Tooth Positive Regulation Of GTPase Activity Cellular Protein Metabolic Process Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing	Negative Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Chromatin Binding Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Mediator Complex Assembly
Pathways		Amyloid fiber formation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS			Blood trace element (Se levels) ( 23720494)
Interacting Genes		13 interacting genes: ADAM15 APP ARID5A HGS IKBKG MED25 POGZ SDCBP SNRPC SPATA31A7 TOLLIP VENTX YPEL3	37 interacting genes: CDK8 CREBBP CTDP1 CYSRT1 ESRP1 EYA2 FAM168B HCFC1 HGS KLHL12 KRTAP6-1 KRTAP6-3 LASP1 MED1 MED15 MED6 MED8 MED9 NCKIPSD NR3C1 ODAM OXER1 PEF1 PLEKHB2 RARA RORB RUSC1 RXRA SERTAD3 SREBF1 STAT5B TFG THRA TLE5 USP54 WWOX WWP2
Entrez ID		54959	81857
HPRD ID		13376	14380
Ensembl ID		ENSG00000109205	ENSG00000104973
Uniprot IDs		A1E959	Q71SY5
PDB IDs			2KY6 2L23 2L6U 2XNF
Enriched GO Terms of Interacting Partners?
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