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TMEM14B and ITGAM
Data Source:
BioGRID
(two hybrid)
TMEM14B
ITGAM
Description
transmembrane protein 14B
integrin subunit alpha M
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrial Inner Membrane
Integral Component Of Membrane
Mitochondrial Membrane
Extracellular Space
Plasma Membrane
Integrin Complex
External Side Of Plasma Membrane
Cell Surface
Integrin AlphaM-beta2 Complex
Specific Granule Membrane
Plasma Membrane Raft
Extracellular Exosome
Tertiary Granule Membrane
Molecular Function
Protein Binding
Identical Protein Binding
Amyloid-beta Binding
Complement Component C3b Binding
Integrin Binding
Protein Binding
Heat Shock Protein Binding
Cargo Receptor Activity
Metal Ion Binding
Biological Process
Mitochondrial Transport
Cerebral Cortex Development
Neural Precursor Cell Proliferation
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Microglial Cell Activation
Receptor-mediated Endocytosis
Phagocytosis, Engulfment
Cell Adhesion
Integrin-mediated Signaling Pathway
Ectodermal Cell Differentiation
Cytokine-mediated Signaling Pathway
Extracellular Matrix Organization
Forebrain Development
Positive Regulation Of Superoxide Anion Generation
Toll-like Receptor 4 Signaling Pathway
Neutrophil Degranulation
Positive Regulation Of Neutrophil Degranulation
Innate Immune Response
Negative Regulation Of Dopamine Metabolic Process
Leukocyte Migration
Positive Regulation Of Protein Targeting To Membrane
Apoptotic Signaling Pathway
Amyloid-beta Clearance
Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Positive Regulation Of Hippocampal Neuron Apoptotic Process
Complement-mediated Synapse Pruning
Vertebrate Eye-specific Patterning
Positive Regulation Of Neuron Death
Positive Regulation Of Microglial Cell Mediated Cytotoxicity
Cell Surface Receptor Signaling Pathway Involved In Cell-cell Signaling
Positive Regulation Of Prostaglandin-E Synthase Activity
Pathways
Toll Like Receptor 4 (TLR4) Cascade
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Interleukin-4 and Interleukin-13 signaling
Neutrophil degranulation
Drugs
Diseases
GWAS
Response to (pegylated) interferon in HBeAg-negative hepatitis B (
30715261
)
Apolipoprotein A1 levels (
32203549
)
Autoimmune thyroid diseases (Graves disease or Hashimoto's thyroiditis) (
22922229
)
Graves' disease (
22922229
)
IgA nephropathy (
25305756
)
Serum metabolite levels (CMS) (
31636271
)
Systemic lupus erythematosus (
27399966
18204446
24871463
26606652
23273568
26502338
18204098
21408207
19165918
28714469
19838195
)
Systemic lupus erythematosus and Systemic sclerosis (
23740937
)
Interacting Genes
229 interacting genes:
ABHD16A
ABHD5
ACSL5
ADAM33
AGPAT3
AGPAT4
AGR3
AGTRAP
APOC2
APOC4
ARL6IP1
ARL8B
ARV1
ATP13A1
B4GALT7
BIK
BLCAP
BMP10
BTN2A2
C10orf67
C14orf180
C1GALT1
C2CD2L
CCL4
CD79A
CEPT1
CFHR5
CIDEB
CLDN10
CLDND2
CMTM5
CMTM8
CNIH2
CNIH3
CNIH4
COMT
CPLX4
CREB3
CREB3L1
CXCL16
CYB561
CYB5R3
DEFB103A
DEFB103B
DGAT2L6
DHRSX
EBP
EI24
EMC6
EPHX4
ERGIC3
EXTL1
FA2H
FADS6
FAM209A
FCER1G
FHL3
FIS1
FKBP8
FXYD6-FXYD2
GDAP1
GIMAP1
GPR152
GPX8
GYPA
GYPC
HEXB
HIBADH
HIGD1C
HMOX1
HMOX2
HSD17B11
HSD3B1
IER3IP1
IFITM3
INSIG2
ITGAM
JAGN1
KCNA1
KCNK1
KHDRBS2
LEPROTL1
LMNA
LPAR3
LRCH1
MAL2
MARCHF5
MEOX2
MFSD12
MFSD5
MGAM
MID2
MMD2
MS4A13
MS4A4A
NAT8
NCALD
NDUFA3
NEU1
NINJ1
NINJ2
NIPAL3
ORMDL1
OTULINL
PAGE1
PDPN
PDZK1IP1
PEX11G
PIGF
PLLP
PLP1
PLP2
PMP22
PNLIPRP1
PPP2R3B
PRAF2
PRH1
PRTFDC1
PSMD3
PTPMT1
RABAC1
RHD
RHOT2
SAR1B
SCAMP5
SCN3B
SCRG1
SERF1A
SERF1B
SERP1
SERP2
SFT2D1
SFT2D2
SFXN1
SFXN2
SFXN3
SLC16A10
SLC16A13
SLC18A1
SLC19A3
SLC2A6
SLC30A3
SLC30A8
SLC35A4
SLC35C2
SLC35E3
SLC35E4
SLC35F1
SLC35F6
SLC35G1
SLC39A2
SLC39A7
SLC48A1
SLC7A8
SMAGP
SMPD2
SPRY2
SQLE
ST6GAL2
STOM
STX12
STX3
STX6
STX8
SUCNR1
SYNGR1
SYNJ2BP
TAP1
TAS2R19
TBC1D20
TEX44
THBD
TIMM22
TIMM23
TIMMDC1
TLCD1
TM4SF4
TMEM11
TMEM120A
TMEM120B
TMEM121
TMEM147
TMEM14A
TMEM14C
TMEM187
TMEM19
TMEM199
TMEM203
TMEM220
TMEM222
TMEM229B
TMEM243
TMEM254
TMEM255B
TMEM267
TMEM42
TMEM50A
TMEM50B
TMEM51
TMEM60
TMEM69
TMEM97
TMIE
TMUB1
TMX2
TOMM6
TSPAN2
TSPO
TVP23B
UBE2J1
UBE2J2
UBE3A
UBIAD1
UBXN8
UNC50
UNC93A
VAMP1
VAMP5
VRK2
VTI1B
YIF1A
YIPF1
YIPF2
YIPF4
YIPF6
ZDHHC11
ZDHHC22
ZDHHC24
ZFPL1
55 interacting genes:
ABHD16A
AQP6
ARL13B
AUP1
C3
CD209
CD79A
CERS4
CFH
CLEC4M
CLRN1
CREB3L1
DKK4
ELANE
ELOVL4
ERGIC3
FGG
GJA8
GJB1
GORAB
GP1BA
GPR42
HP
HSD17B13
ICAM1
ICAM2
ICAM4
IRAK1
ITGB2
JAM3
KASH5
KCNJ6
KIR2DL3
LMNA
MGST3
MMGT1
MRM1
MUC1
PGRMC2
PIGP
PLAUR
REEP2
REEP4
RUSF1
SCN3B
SHARPIN
SLC10A6
SLC35C2
SYT2
THY1
TMEM14B
TMEM229B
TMEM31
TMEM52B
TMX2
Entrez ID
81853
3684
HPRD ID
15523
00411
Ensembl ID
ENSG00000137210
ENSG00000169896
Uniprot IDs
A0A024QZV7
A0A087WU83
C9JCY4
C9JQS0
Q9NUH8
P11215
PDB IDs
1A8X
1BHO
1BHQ
1IDN
1IDO
1JLM
1M1U
1MF7
1N9Z
1NA5
2LKE
2LKJ
3Q3G
3QA3
4M76
4XW2
6RHW
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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