RAB11B and RAB11FIP2

Data Source:
HPRD (two hybrid)

		RAB11B	RAB11FIP2
Description		RAB11B, member RAS oncogene family	RAB11 family interacting protein 2
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GO Annotations	Cellular Component	Endosome Cytosol Synaptic Vesicle Phagocytic Vesicle Membrane Phagocytic Vesicle Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane	Phagocytic Cup Nucleoplasm Endosome Cytoplasmic Vesicle Membrane Cell Projection Intracellular Membrane-bounded Organelle Recycling Endosome Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding Cadherin Binding	Protein Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Receptor Recycling Exocytosis Melanosome Transport Transferrin Transport Insulin Secretion Involved In Cellular Response To Glucose Stimulus Post-translational Protein Modification Regulation Of Anion Transport Constitutive Secretory Pathway Regulated Exocytosis Cellular Response To Acidic PH Establishment Of Protein Localization To Membrane Amyloid-beta Clearance By Transcytosis Retrograde Transport, Endosome To Plasma Membrane Regulation Of Protein Localization To Cell Surface Regulation Of Endocytic Recycling	Renal Water Homeostasis Phagocytosis Establishment Of Cell Polarity TRAM-dependent Toll-like Receptor 4 Signaling Pathway Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of GTPase Activity Regulated Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		TBC/RABGAPs RAB geranylgeranylation	Vasopressin regulates renal water homeostasis via Aquaporins
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494)	Age spots ( 29895819) Asthma (sex interaction) ( 24824216) Celiac disease ( 23936387) Freckles ( 29895819) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 30993211 29403010)
Interacting Genes		11 interacting genes: APP IKBKG MEOX2 MYO5B OPTN RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP5 SH3BP5L SREBF2	20 interacting genes: AP2A1 CXCR2 EHD1 FAM90A1 FBXO17 FKBP6 HSF2BP ITSN1 KANK2 LRRK2 MARK2 MYO5B PIBF1 RAB11A RAB11B RAB11FIP4 RAB25 REPS1 YWHAE YWHAG
Entrez ID		9230	22841
HPRD ID		05009	10548
Ensembl ID		ENSG00000185236	ENSG00000107560
Uniprot IDs		Q15907	Q7L804
PDB IDs		2F9L 2F9M 4OJK	2GZD 2GZH 2K6S 3TSO 4C4P 6S8X
Enriched GO Terms of Interacting Partners?
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