RAB14 and RUFY1

Data Source:
BioGRID (two hybrid, pull down)

		RAB14	RUFY1
Description		RAB14, member RAS oncogene family	RUN and FYVE domain containing 1
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GO Annotations	Cellular Component	Golgi Membrane Lysosome Lysosomal Membrane Early Endosome Late Endosome Rough Endoplasmic Reticulum Golgi Stack Trans-Golgi Network Cytosol Plasma Membrane Cilium Endomembrane System Trans-Golgi Network Transport Vesicle Early Endosome Membrane Nuclear Outer Membrane-endoplasmic Reticulum Membrane Network Intracellular Membrane-bounded Organelle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Tertiary Granule Membrane	Cytoplasm Endosome Cytosol Nuclear Speck Early Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding	Protein Binding Lipid Binding SH3 Domain Binding SH2 Domain Binding Metal Ion Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Intracellular Protein Transport Golgi To Endosome Transport Fibroblast Growth Factor Receptor Signaling Pathway Vesicle-mediated Transport Endocytic Recycling Regulation Of Protein Localization Defense Response To Bacterium Neutrophil Degranulation Regulation Of Embryonic Development Intracellular Transport Phagolysosome Assembly Involved In Apoptotic Cell Clearance	Phosphatidylinositol Biosynthetic Process Endocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Endocytosis
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Synthesis of PIPs at the plasma membrane Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)	Daytime sleep phenotypes ( 27126917) Dental caries (decayed and filled deciduous teeth) ( 31533690) Eating disorders ( 22911880) Lung cancer ( 28604730) Monocyte percentage of white cells ( 32888494) TPE interval (resting) ( 32386560)
Interacting Genes		12 interacting genes: ADRB2 APP CHM EXOC5 FAM71C OCRL OPTN RAB11FIP5 RBSN RUFY1 SH3BP5L SMURF2	18 interacting genes: AP3B2 AP3D1 AP3M1 AP3S1 BMX EPHA3 GIT2 ITSN2 OAS1 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TRIM23 TXNDC17 UTP25
Entrez ID		51552	80230
HPRD ID		06693	15282
Ensembl ID		ENSG00000119396	ENSG00000176783
Uniprot IDs		A0A024R845 P61106	A8K7B1 Q96T51
PDB IDs		1Z0F 4D0G 4DRZ	2YQM 2YW8
Enriched GO Terms of Interacting Partners?
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