PDCD1LG2 and LRP10

Data Source:
BioGRID (two hybrid)

		PDCD1LG2	LRP10
Description		programmed cell death 1 ligand 2	LDL receptor related protein 10
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Endomembrane System Integral Component Of Membrane	Clathrin-coated Pit Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function Protein Binding	Low-density Lipoprotein Particle Receptor Activity Protein Binding
	Biological Process	Adaptive Immune Response Immune Response Cell Surface Receptor Signaling Pathway T Cell Costimulation Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-10 Production Positive Regulation Of T Cell Proliferation Negative Regulation Of T Cell Proliferation Negative Regulation Of Activated T Cell Proliferation Cellular Response To Lipopolysaccharide	Lipid Metabolic Process Lipid Transport Endocytosis Inner Ear Development
Pathways		PD-1 signaling	Retinoid metabolism and transport
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269)	Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) Neutrophil count ( 32888494)
Interacting Genes		20 interacting genes: ATP6V0C ERMP1 GALNT15 GPR37L1 KTN1 LRP10 MFSD6 PDCD1 RUSF1 SLC35C2 SLC38A1 SLC38A7 SLC41A2 SLC7A1 SMIM3 TAS2R10 TMEM147 TMEM218 TMEM239 TMEM97	23 interacting genes: C16orf92 CISD2 EBP FAM209A GGA3 GJB5 GOLM2 GORAB HTRA1 LMNA MFSD14B MGST3 MRPS18B NOTO PDCD1LG2 PLEKHO1 SLC10A1 SLC14A2 SMIM1 ST6GALNAC6 TMEM179B TMEM237 TMEM243
Entrez ID		80380	26020
HPRD ID		16147	14311
Ensembl ID		ENSG00000197646	ENSG00000197324
Uniprot IDs		Q9BQ51	Q7Z4F1
PDB IDs		6UMT
Enriched GO Terms of Interacting Partners?
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