PDCD1LG2 and SLC41A2

Data Source:
BioGRID (two hybrid)

		PDCD1LG2	SLC41A2
Description		programmed cell death 1 ligand 2	solute carrier family 41 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Endomembrane System Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function Protein Binding	Protein Binding Inorganic Cation Transmembrane Transporter Activity
	Biological Process	Adaptive Immune Response Immune Response Cell Surface Receptor Signaling Pathway T Cell Costimulation Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-10 Production Positive Regulation Of T Cell Proliferation Negative Regulation Of T Cell Proliferation Negative Regulation Of Activated T Cell Proliferation Cellular Response To Lipopolysaccharide	Metal Ion Transport Cation Transmembrane Transport
Pathways		PD-1 signaling	Metal ion SLC transporters
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269)	Beta blocker survival benefit in heart failure with reduced ejection fraction (time to all cause mortality x beta blocker interaction) ( 33012170)
Interacting Genes		20 interacting genes: ATP6V0C ERMP1 GALNT15 GPR37L1 KTN1 LRP10 MFSD6 PDCD1 RUSF1 SLC35C2 SLC38A1 SLC38A7 SLC41A2 SLC7A1 SMIM3 TAS2R10 TMEM147 TMEM218 TMEM239 TMEM97	31 interacting genes: AQP6 CD79A CLN5 CREB3 EBP ERGIC3 ERVFRD-1 FATE1 FNDC9 FUT3 GJA5 GJB5 GPR151 GPR42 GPX8 IGFBP5 IL27RA KASH5 KIR3DL3 LDLRAD1 LEUTX LIME1 LMNA LY6G6C LYVE1 MFF PDCD1LG2 PVR SHISAL1 SSMEM1 TMEM237
Entrez ID		80380	84102
HPRD ID		16147	15389
Ensembl ID		ENSG00000197646	ENSG00000136052
Uniprot IDs		Q9BQ51	Q96JW4
PDB IDs		6UMT
Enriched GO Terms of Interacting Partners?
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