LRP10 and NOTO

Data Source:
BioGRID (two hybrid)

		LRP10	NOTO
Description		LDL receptor related protein 10	notochord homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Clathrin-coated Pit Membrane Integral Component Of Membrane	Chromatin Nucleus
	Molecular Function	Low-density Lipoprotein Particle Receptor Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Lipid Metabolic Process Lipid Transport Endocytosis Inner Ear Development	Heart Looping Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Embryonic Pattern Specification Dorsal/ventral Pattern Formation Neuron Differentiation Notochord Development Motile Cilium Assembly Regulation Of Cilium Assembly
Pathways		Retinoid metabolism and transport
Drugs
Diseases
GWAS		Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) Neutrophil count ( 32888494)	General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435)
Interacting Genes		23 interacting genes: C16orf92 CISD2 EBP FAM209A GGA3 GJB5 GOLM2 GORAB HTRA1 LMNA MFSD14B MGST3 MRPS18B NOTO PDCD1LG2 PLEKHO1 SLC10A1 SLC14A2 SMIM1 ST6GALNAC6 TMEM179B TMEM237 TMEM243	31 interacting genes: ANKRD11 APOBEC1 BAG3 BANP BTF3 CCDC120 CEP19 CHAF1A EIPR1 ETV3L FAM9B FOXD2 FOXH1 GLYCTK HNRNPK IP6K3 KRT34 KRTAP19-7 KRTAP5-6 KRTAP6-1 KRTAP6-3 LDLRAP1 LRP10 MAGED1 MEIS2 NKX2-4 PIH1D2 POU4F2 SBK3 TTC23 UBTFL1
Entrez ID		26020	344022
HPRD ID		14311
Ensembl ID		ENSG00000197324	ENSG00000214513
Uniprot IDs		Q7Z4F1	A8MTQ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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