PDCD1LG2 and TMEM97

Data Source:
BioGRID (two hybrid)

		PDCD1LG2	TMEM97
Description		programmed cell death 1 ligand 2	transmembrane protein 97
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Endomembrane System Integral Component Of Membrane	Lysosome Endoplasmic Reticulum Rough Endoplasmic Reticulum Plasma Membrane Integral Component Of Membrane Rough Endoplasmic Reticulum Membrane Nuclear Membrane
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Adaptive Immune Response Immune Response Cell Surface Receptor Signaling Pathway T Cell Costimulation Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-10 Production Positive Regulation Of T Cell Proliferation Negative Regulation Of T Cell Proliferation Negative Regulation Of Activated T Cell Proliferation Cellular Response To Lipopolysaccharide	Regulation Of Cell Growth Cholesterol Homeostasis
Pathways		PD-1 signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269)	Advanced age-related macular degeneration ( 26691988) Blood protein levels ( 29875488) Osteoprotegerin levels ( 25080503)
Interacting Genes		20 interacting genes: ATP6V0C ERMP1 GALNT15 GPR37L1 KTN1 LRP10 MFSD6 PDCD1 RUSF1 SLC35C2 SLC38A1 SLC38A7 SLC41A2 SLC7A1 SMIM3 TAS2R10 TMEM147 TMEM218 TMEM239 TMEM97	61 interacting genes: APP AQP12B AQP2 AQP6 ARL13B ASZ1 ATP6AP2 BCL2L13 BIK CD53 CD74 CGRRF1 CLDN7 CLSTN3 CPLX4 EBP ERGIC3 FAM209A FFAR2 FKBP7 FRMD3 FXYD3 GJB3 GJB5 GPR152 GPR37L1 GPX8 HSD17B13 IFNGR2 KIR2DL3 LEUTX LHFPL5 LIME1 LRRC59 MFF MRM1 MTIF3 MUC1 NDUFAF1 NDUFAF2 NEMP1 PDCD1LG2 PDZK1IP1 PLP1 PSCA REEP1 RHCG RNF170 SAR1A SGPL1 SLC14A1 SLC14A2 SPINT1 SSMEM1 TMEM106C TMEM14B TMEM45B TMEM52B TMEM79 TMX2 VSIR
Entrez ID		80380	27346
HPRD ID		16147	14343
Ensembl ID		ENSG00000197646	ENSG00000109084
Uniprot IDs		Q9BQ51	Q5BJF2
PDB IDs		6UMT
Enriched GO Terms of Interacting Partners?
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