CEP76 and GFAP

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CEP76	GFAP
Description		centrosomal protein 76	glial fibrillary acidic protein
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol Protein-containing Complex	Cytoplasm Lysosome Cytosol Intermediate Filament Intermediate Filament Cytoskeleton
	Molecular Function	Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Identical Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Centriole Replication Ciliary Basal Body-plasma Membrane Docking	Regulation Of Protein-containing Complex Assembly Intermediate Filament Organization Regulation Of Chaperone-mediated Autophagy
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Nuclear signaling by ERBB4 Chaperone Mediated Autophagy
Drugs
Diseases			Alexander disease
GWAS			Asthma ( 31619474) Cognitive function ( 25644384) Craniofacial microsomia ( 26853712)
Interacting Genes		105 interacting genes: AKAP7 AKT1 ANKRD36 ASH2L BANP C22orf39 CABP5 CACNB3 CAPN3 CAVIN3 CCDC92 CCNK CDK18 CENPI CIR1 COIL CRYBA4 CSNK1G1 CUTC CWF19L2 DCTD DDX6 DEAF1 DMTN DVL3 DZIP1L EAF1 EIF1AD EP400P1 ERCC3 FAM90A1 GDAP2 GFAP GORASP2 HSF2 HSPB7 ILVBL IQUB KDM1A KDM4D KIAA1143 KIFBP KLHDC4 L3MBTL2 LATS1 LNX1 MAGEA11 MBD3 MFAP1 MISP MLH1 MYOZ1 NEK6 NFYC NHLRC2 NME5 PAICS PARD6B PATZ1 PDGFRB PDRG1 PDZD4 PDZD7 PIN1 PKP1 PLA2G6 PLCB1 POM121 RADIL RALGPS1 RBM41 RIPPLY3 RNF128 RPL9 SALL2 SCNM1 SH2D4A SINHCAF SMG9 SPG21 STK26 SUOX TBC1D27P TCEA2 TCEANC TCF19 TFAP2D THRA TOB2 TSPOAP1 TSSC4 TTC21A TTLL10 TUFT1 TXNDC9 VEZF1 WDFY3 YY1 ZBTB24 ZBTB4 ZMAT2 ZNF185 ZNF653 ZNF76 ZNF85	80 interacting genes: ABI2 AKT1 APP AURKB BIRC2 CAMK2A CARD10 CCDC57 CDC37 CDK1 CEP76 CFAP206 CRYAB CT55 CWF19L2 DES ENKD1 EPM2AIP1 FAM50B GOLGA2 GRAP2 HGS HOMEZ IKBKG KIAA0408 KRT13 KRT15 KRT19 KRT27 KRT31 KRT39 LENG1 LGALS14 LMO2 MAPK9 MEN1 MOS MYBPHL MYO15B NEFL NEK6 NFKBID NTAQ1 NXF1 PDLIM1 PDLIM7 PDZK1 PIAS2 PIH1D2 POM121 PPP1R16B PPP1R18 PRKACA PRKCA PRKCG PSEN1 PSEN2 RIBC2 ROCK1 RORA S100A1 S100B SH3YL1 SMARCB1 SRC STAT1 TBC1D21 TBC1D22B TFIP11 TLE5 TP53BP2 TRIM27 TUBGCP4 UBASH3A UBE3A VIM YES1 ZC2HC1C ZNF655 ZNF774
Entrez ID		79959	2670
HPRD ID		12694	00675
Ensembl ID		ENSG00000101624	ENSG00000131095
Uniprot IDs		B4DP81 Q8TAP6	A7REI1 P14136
PDB IDs			6A9P
Enriched GO Terms of Interacting Partners?
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