CEP76 and TCF19

Data Source:
BioGRID (two hybrid)

		CEP76	TCF19
Description		centrosomal protein 76	transcription factor 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol Protein-containing Complex	Nucleus
	Molecular Function	Protein Binding	DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Centriole Replication Ciliary Basal Body-plasma Membrane Docking	Regulation Of Transcription, DNA-templated Regulation Of Gene Expression
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS			Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Chronic hepatitis B infection ( 25802187 23760081) Idiopathic membranous nephropathy ( 21323541) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Marginal zone lymphoma ( 25569183) Multiple myeloma ( 23955597) Night sleep phenotypes ( 27126917) Refractive error ( 32231278) Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) ( 21912425) Type 2 diabetes ( 24509480 30718926) Ulcerative colitis ( 28067908) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		105 interacting genes: AKAP7 AKT1 ANKRD36 ASH2L BANP C22orf39 CABP5 CACNB3 CAPN3 CAVIN3 CCDC92 CCNK CDK18 CENPI CIR1 COIL CRYBA4 CSNK1G1 CUTC CWF19L2 DCTD DDX6 DEAF1 DMTN DVL3 DZIP1L EAF1 EIF1AD EP400P1 ERCC3 FAM90A1 GDAP2 GFAP GORASP2 HSF2 HSPB7 ILVBL IQUB KDM1A KDM4D KIAA1143 KIFBP KLHDC4 L3MBTL2 LATS1 LNX1 MAGEA11 MBD3 MFAP1 MISP MLH1 MYOZ1 NEK6 NFYC NHLRC2 NME5 PAICS PARD6B PATZ1 PDGFRB PDRG1 PDZD4 PDZD7 PIN1 PKP1 PLA2G6 PLCB1 POM121 RADIL RALGPS1 RBM41 RIPPLY3 RNF128 RPL9 SALL2 SCNM1 SH2D4A SINHCAF SMG9 SPG21 STK26 SUOX TBC1D27P TCEA2 TCEANC TCF19 TFAP2D THRA TOB2 TSPOAP1 TSSC4 TTC21A TTLL10 TUFT1 TXNDC9 VEZF1 WDFY3 YY1 ZBTB24 ZBTB4 ZMAT2 ZNF185 ZNF653 ZNF76 ZNF85	19 interacting genes: APP BLZF1 CEP76 DNAJA3 GOLGA2 H3-4 H4-16 HOXA1 HSF2BP LZTR1 NFKBID NOXA1 PDLIM7 PFDN5 PRKAB2 RHOH TRIB3 UBE3A ZNF474
Entrez ID		79959	6941
HPRD ID		12694	15986
Ensembl ID		ENSG00000101624	ENSG00000137310
Uniprot IDs		B4DP81 Q8TAP6	A0A1U9X8M7 Q9Y242
PDB IDs
Enriched GO Terms of Interacting Partners?
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