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ZNF408 and AEN
Data Source:
BioGRID
(two hybrid)
ZNF408
AEN
Description
zinc finger protein 408
apoptosis enhancing nuclease
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleus
Nucleoplasm
Nucleolus
Nuclear Membrane
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Identical Protein Binding
Metal Ion Binding
Nucleic Acid Binding
Exonuclease Activity
Protein Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Response To Ionizing Radiation
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS
Alzheimer's disease or fasting glucose levels (pleiotropy) (
30805717
)
Autism spectrum disorder or schizophrenia (
28540026
)
Femoral neck bone mineral density (
29499414
)
Schizophrenia (
29483656
)
Dupuytren's disease (
28886342
)
Night sleep phenotypes (
27126917
)
Interacting Genes
83 interacting genes:
AEBP2
AEN
APOBEC3C
ATRN
BAHD1
CALCOCO2
CCDC136
CEP70
CHAF1A
CRELD1
CYSRT1
DDX56
DVL3
EXOSC2
FBLN2
FHL2
FHL5
FSD2
GIPC1
GPATCH2L
HNRNPK
HOXA5
HOXB9
ID3
KCTD9
KHDRBS3
KRT40
KRTAP1-1
KRTAP10-7
KRTAP10-8
KRTAP12-2
KRTAP12-3
KRTAP4-12
KRTAP5-9
LDOC1
LSM2
LZTS2
MDFI
MID2
MIF
MRRF
MTUS2
NBPF19
NOTCH2NLA
PDE4DIP
PDLIM4
PICK1
PNMA2
PRAME
PRNP
PRPF31
PSTPIP1
RALY
RALYL
RBM10
RBMY1F
RBMY1J
SAP30BP
SPRED1
SSX2IP
THAP1
TLE5
TOP3B
TRIM23
TRIM41
UBE2I
UPF2
USP20
ZBTB26
ZBTB48
ZBTB8A
ZBTB9
ZC4H2
ZNF212
ZNF317
ZNF330
ZNF331
ZNF473
ZNF526
ZNF764
ZNF792
ZNF837
ZRANB1
37 interacting genes:
AAMP
EMD
EXOSC8
GNPTAB
HAP1
HOMEZ
IKZF1
KANK2
KHDRBS2
KRT40
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
LZTS2
MBNL1
MID2
MTUS2
NKX3-1
PDE4DIP
PHC2
RALYL
RBMY1A1
RBMY1F
RPGRIP1
SPOP
SSX2IP
TLE5
TRIM27
TRIM41
ZBTB43
ZBTB8A
ZFP64
ZNF317
ZNF408
ZNF473
Entrez ID
79797
64782
HPRD ID
18338
08573
Ensembl ID
ENSG00000175213
ENSG00000181026
Uniprot IDs
B4DXY4
Q9H9D4
Q8WTP8
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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