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ZNF408 and THAP1
Data Source:
BioGRID
(two hybrid, two hybrid)
HPRD
(two hybrid)
ZNF408
THAP1
Description
zinc finger protein 408
THAP domain containing 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Chromatin
Fibrillar Center
Nucleus
Nucleoplasm
PML Body
Intracellular Membrane-bounded Organelle
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Identical Protein Binding
Metal Ion Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Identical Protein Binding
Protein Homodimerization Activity
Sequence-specific DNA Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Transcription By RNA Polymerase II
Endothelial Cell Proliferation
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Cell Cycle
Regulation Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
Primary torsion dystonia (PTD)
GWAS
Alzheimer's disease or fasting glucose levels (pleiotropy) (
30805717
)
Autism spectrum disorder or schizophrenia (
28540026
)
Femoral neck bone mineral density (
29499414
)
Schizophrenia (
29483656
)
Pelvic organ prolapse (moderate/severe) (
26545240
)
Interacting Genes
83 interacting genes:
AEBP2
AEN
APOBEC3C
ATRN
BAHD1
CALCOCO2
CCDC136
CEP70
CHAF1A
CRELD1
CYSRT1
DDX56
DVL3
EXOSC2
FBLN2
FHL2
FHL5
FSD2
GIPC1
GPATCH2L
HNRNPK
HOXA5
HOXB9
ID3
KCTD9
KHDRBS3
KRT40
KRTAP1-1
KRTAP10-7
KRTAP10-8
KRTAP12-2
KRTAP12-3
KRTAP4-12
KRTAP5-9
LDOC1
LSM2
LZTS2
MDFI
MID2
MIF
MRRF
MTUS2
NBPF19
NOTCH2NLA
PDE4DIP
PDLIM4
PICK1
PNMA2
PRAME
PRNP
PRPF31
PSTPIP1
RALY
RALYL
RBM10
RBMY1F
RBMY1J
SAP30BP
SPRED1
SSX2IP
THAP1
TLE5
TOP3B
TRIM23
TRIM41
UBE2I
UPF2
USP20
ZBTB26
ZBTB48
ZBTB8A
ZBTB9
ZC4H2
ZNF212
ZNF317
ZNF330
ZNF331
ZNF473
ZNF526
ZNF764
ZNF792
ZNF837
ZRANB1
105 interacting genes:
ABCF3
ACOT7
AEBP2
AKAP17A
AKAP9
AP2B1
APP
ARL6IP4
BAG5
BEND7
BMS1P1
BYSL
C1orf216
C1orf35
C4orf45
C7orf50
CDC37
CDKN2D
CHD2
CSNK2A1
DCAF8
DVL2
EEF1AKNMT
FAM124A
FAM133A
FAM9A
FGF10
FGF11
FGF12
FXR2
GAS8
GPATCH2L
HNRNPLL
HYPK
INO80B
KANK2
KLF12
KRTAP10-7
L3MBTL2
LASP1
LMNB2
LMO3
LNX1
MFAP1
MIS18A
MORF4L1
MORF4L2
MRPL11
MRPL53
NDUFAB1
NKAP
NKAPD1
NTAQ1
NUP62
PAWR
PHF1
PHF19
PID1
PNKP
POLR2L
POLR2M
POU6F2
PPIG
PRKAA1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
QKI
RAD54L2
RALY
RALYL
RBM10
RBM39
RIPPLY1
RNF4
RP9P
RPL22
RPS25
SAP30BP
SERF2
SLU7
SPANXN2
SREK1IP1
STRBP
TCEA2
TCEANC
TPM3
TRAF5
TRIM26
TRIP10
TTLL10
TXN2
U2AF2
UBE2I
VCX2
WT1
YES1
ZBTB48
ZCCHC10
ZGPAT
ZNF385C
ZNF408
ZNF526
Entrez ID
79797
55145
HPRD ID
18338
15496
Ensembl ID
ENSG00000175213
ENSG00000131931
Uniprot IDs
B4DXY4
Q9H9D4
Q9NVV9
PDB IDs
2JTG
2KO0
2L1G
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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