AEN and ZFP64

Data Source:
BioGRID (two hybrid, two hybrid)

		AEN	ZFP64
Description		apoptosis enhancing nuclease	ZFP64 zinc finger protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Membrane	Nucleus
	Molecular Function	Nucleic Acid Binding Exonuclease Activity Protein Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Nucleic Acid Phosphodiester Bond Hydrolysis	Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Dupuytren's disease ( 28886342) Night sleep phenotypes ( 27126917)	Adult body size ( 32376654) Amyotrophic lateral sclerosis ( 17362836) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 28892062 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Parkinson's disease ( 26227905) Reading disability or specific language impairment (pleiotropy) ( 25065397) Subcutaneous adipose tissue ( 22589738) Urinary metabolite levels in chronic kidney disease ( 29545352) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) Waist circumference ( 25673412) Waist-hip ratio ( 25673412)
Interacting Genes		37 interacting genes: AAMP EMD EXOSC8 GNPTAB HAP1 HOMEZ IKZF1 KANK2 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SPOP SSX2IP TLE5 TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF408 ZNF473	27 interacting genes: AEN BARD1 BEGAIN BYSL EMD ERG28 FAM124A FHL2 L3MBTL2 LMO2 LNX1 MAFB MFAP1 MTUS2 PBK PPARGC1B PRPF31 RBM10 RHOU SETDB1 TAB2 TLE1 TRIM41 UNC119 ZBTB9 ZNF513 ZNF70
Entrez ID		64782	55734
HPRD ID		08573	15728
Ensembl ID		ENSG00000181026	ENSG00000020256
Uniprot IDs		Q8WTP8	B3KQX0 Q9NTW7
PDB IDs			1X5W 2DMD
Enriched GO Terms of Interacting Partners?
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