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FAM118B and GNB2
Data Source:
BioGRID
(two hybrid)
FAM118B
GNB2
Description
family with sequence similarity 118 member B
G protein subunit beta 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cajal Body
Extracellular Space
Cytoplasm
Lysosomal Membrane
Cytosol
Heterotrimeric G-protein Complex
Plasma Membrane
Focal Adhesion
Membrane
Vesicle
Cell Body
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Molecular Function
Protein Binding
Identical Protein Binding
GTPase Activity
Calcium Channel Regulator Activity
Protein Binding
G-protein Gamma-subunit Binding
Protein-containing Complex Binding
GTPase Binding
Biological Process
Cajal Body Organization
Protein Folding
G Protein-coupled Receptor Signaling Pathway
Pathways
Activation of G protein gated Potassium channels
Glucagon signaling in metabolic regulation
G-protein activation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
G beta:gamma signalling through BTK
G beta:gamma signalling through CDC42
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Diseases
GWAS
Hematocrit (
27863252
)
Hemoglobin concentration (
27863252
)
Hemoglobin levels (
32327693
)
Interacting Genes
29 interacting genes:
BAG5
CEP126
CEP70
CTSB
FAM118A
FAM20C
GNB2
ING5
ITFG1
MCM3AP
MED31
NGEF
PDCD10
PIAS2
QARS1
RAD54L2
RASGRP2
RBM48
SDCBP
SEMA5B
SETDB1
SHC1
SPRED1
SUMO1
SUMO1P1
TMSB4X
VIM
ZNF235
ZNF746
33 interacting genes:
ANXA7
ATXN10
CAPNS1
CDKN1A
CSNK1A1
FAM118B
FANCA
GADD45A
GNAI1
GNAI2
GNAI3
GNG10
GNG12
GNG13
GNG3
GNG4
GNG5
GNG7
GNGT1
GRB7
GRK2
GSK3B
ID3
MTNR1B
NR3C1
PCBP1
PDHB
RAF1
RASD2
RCC1
STAT5A
TGFBR1
TSC22D1
Entrez ID
79607
2783
HPRD ID
07952
11820
Ensembl ID
ENSG00000197798
ENSG00000172354
Uniprot IDs
A0A024R3L8
J3KP39
Q9BPY3
P62879
Q6FHM2
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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