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GNB2 and GNAI1
Data Source:
BioGRID
(fluorescent resonance energy transfer)
GNB2
GNAI1
Description
G protein subunit beta 2
G protein subunit alpha i1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Cytoplasm
Lysosomal Membrane
Cytosol
Heterotrimeric G-protein Complex
Plasma Membrane
Focal Adhesion
Membrane
Vesicle
Cell Body
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Nucleus
Cytoplasm
Lysosomal Membrane
Centrosome
Heterotrimeric G-protein Complex
Plasma Membrane
Midbody
Membrane Raft
Extracellular Exosome
Cell Cortex Region
Molecular Function
GTPase Activity
Calcium Channel Regulator Activity
Protein Binding
G-protein Gamma-subunit Binding
Protein-containing Complex Binding
GTPase Binding
Magnesium Ion Binding
G Protein-coupled Receptor Binding
GTPase Activity
Protein Binding
GTP Binding
GDP Binding
G-protein Beta/gamma-subunit Complex Binding
G Protein-coupled Serotonin Receptor Binding
GTPase Activating Protein Binding
Biological Process
Protein Folding
G Protein-coupled Receptor Signaling Pathway
Protein Folding
Cell Cycle
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Response To Peptide Hormone
Regulation Of CAMP-mediated Signaling
Negative Regulation Of Synaptic Transmission
Cell Division
Regulation Of Mitotic Spindle Organization
Cellular Response To Forskolin
Positive Regulation Of Protein Localization To Cell Cortex
Pathways
Activation of G protein gated Potassium channels
Glucagon signaling in metabolic regulation
G-protein activation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
G beta:gamma signalling through BTK
G beta:gamma signalling through CDC42
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
PLC beta mediated events
PLC beta mediated events
Adenylate cyclase inhibitory pathway
Adenylate cyclase inhibitory pathway
G-protein activation
ADP signalling through P2Y purinoceptor 12
Adrenaline,noradrenaline inhibits insulin secretion
Adrenaline,noradrenaline inhibits insulin secretion
G alpha (s) signalling events
G alpha (i) signalling events
G alpha (i) signalling events
G alpha (z) signalling events
Regulation of insulin secretion
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Drugs
Guanosine-5'-Diphosphate
Tetrafluoroaluminate Ion
Diseases
GWAS
Hematocrit (
27863252
)
Hemoglobin concentration (
27863252
)
Hemoglobin levels (
32327693
)
Cognitive decline rate in late mild cognitive impairment (
26252872
)
Emphysema annual change measurement in smokers (adjusted lung density) (
31324189
)
Night sleep phenotypes (
27126917
)
Post bronchodilator FEV1 (
26634245
)
Interacting Genes
33 interacting genes:
ANXA7
ATXN10
CAPNS1
CDKN1A
CSNK1A1
FAM118B
FANCA
GADD45A
GNAI1
GNAI2
GNAI3
GNG10
GNG12
GNG13
GNG3
GNG4
GNG5
GNG7
GNGT1
GRB7
GRK2
GSK3B
ID3
MTNR1B
NR3C1
PCBP1
PDHB
RAF1
RASD2
RCC1
STAT5A
TGFBR1
TSC22D1
62 interacting genes:
ADCY5
ADRA2A
ADRB2
CCR5
CD47
CNR1
CRHR1
CXCR4
DRD3
DRD4
EPOR
ESR1
FFAR1
GNAO1
GNB2
GNB4
GNG2
GPR1
GPR143
GPSM1
GPSM2
GPSM3
HRH4
HTR2A
IGF1R
KLHL3
MTNR1A
MTNR1B
NGB
NUCB1
NUMA1
OPRD1
OPRM1
PCP2
PDE6D
PTEN
PTPRU
RANGAP1
RASD1
RGS10
RGS12
RGS14
RGS16
RGS17
RGS18
RGS19
RGS20
RGS4
RGS7
RIC8A
S1PR1
S1PR2
S1PR3
S1PR4
S1PR5
SSTR2
SSTR3
STRN
THAP7
TSHR
VIPR1
WASF1
Entrez ID
2783
2770
HPRD ID
11820
00756
Ensembl ID
ENSG00000172354
ENSG00000127955
Uniprot IDs
P62879
Q6FHM2
P63096
PDB IDs
1KJY
1Y3A
2G83
2GTP
2IK8
2OM2
2XNS
3ONW
3QE0
3QI2
3UMR
3UMS
4G5Q
5JS7
5JS8
5TDH
6CMO
6CRK
6DDE
6DDF
6KPF
6KPG
6LFM
6LFO
6LML
6N4B
6OMM
6OS9
6OSA
6OT0
6PB0
6PB1
6PT0
6QNO
6VU8
6XBJ
6XBK
6XBL
6XBM
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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