FAM118B and ZNF746

Data Source:
BioGRID (two hybrid)

		FAM118B	ZNF746
Description		family with sequence similarity 118 member B	zinc finger protein 746
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cajal Body	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Identical Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding
	Biological Process	Cajal Body Organization	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Death
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS			Amyotrophic lateral sclerosis ( 19451621) Multiple sclerosis ( 21833088)
Interacting Genes		29 interacting genes: BAG5 CEP126 CEP70 CTSB FAM118A FAM20C GNB2 ING5 ITFG1 MCM3AP MED31 NGEF PDCD10 PIAS2 QARS1 RAD54L2 RASGRP2 RBM48 SDCBP SEMA5B SETDB1 SHC1 SPRED1 SUMO1 SUMO1P1 TMSB4X VIM ZNF235 ZNF746	14 interacting genes: DIABLO DUSP23 EPHA8 FAM118B FES GSK3B HMOX2 ILK MAP3K20 MAP3K7 PRKN PRKRA RPS6KA6 UBE2E3
Entrez ID		79607	155061
HPRD ID		07952	08099
Ensembl ID		ENSG00000197798	ENSG00000181220
Uniprot IDs		A0A024R3L8 J3KP39 Q9BPY3	Q6NUN9
PDB IDs
Enriched GO Terms of Interacting Partners?
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