FAM118B and ING5

Data Source:
BioGRID (two hybrid)

		FAM118B	ING5
Description		family with sequence similarity 118 member B	inhibitor of growth family member 5
Image		No pdb structure
GO Annotations	Cellular Component	Cajal Body	Histone Acetyltransferase Complex Nucleus Nucleoplasm Chromosome MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Protein Binding Identical Protein Binding	Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	Cajal Body Organization	DNA Replication Protein Acetylation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Apoptotic Signaling Pathway
Pathways			HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS			Asthma ( 31959851) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Platelet distribution width ( 32888494)
Interacting Genes		29 interacting genes: BAG5 CEP126 CEP70 CTSB FAM118A FAM20C GNB2 ING5 ITFG1 MCM3AP MED31 NGEF PDCD10 PIAS2 QARS1 RAD54L2 RASGRP2 RBM48 SDCBP SEMA5B SETDB1 SHC1 SPRED1 SUMO1 SUMO1P1 TMSB4X VIM ZNF235 ZNF746	47 interacting genes: APC APLP1 ARFIP2 BARD1 BEX3 BRPF1 C3orf62 CBY2 CCDC33 CCHCR1 CDCA7L CDK2 CDKN1A CEP126 CEP44 DEUP1 EP300 FAM118B GCSH GGA1 GRIPAP1 HAP1 HGS HTT ICA1 IKZF3 JADE2 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 ODF2 PCM1 PRMT5 RCOR3 SMARCE1 SUOX TADA3 TAF1D THAP6 TP53 TRIML2 VIM WASF1
Entrez ID		79607	84289
HPRD ID		07952	16348
Ensembl ID		ENSG00000197798	ENSG00000168395
Uniprot IDs		A0A024R3L8 J3KP39 Q9BPY3	A0A1B0GW41 Q8WYH8
PDB IDs			3C6W 5ME8 5MTO
Enriched GO Terms of Interacting Partners?
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