EPM2A and NFU1

		EPM2A	NFU1
Description		EPM2A glucan phosphatase, laforin	NFU1 iron-sulfur cluster scaffold
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GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding	Iron Ion Binding Protein Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Positive Regulation Of Macroautophagy Negative Regulation Of TOR Signaling	Iron-sulfur Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer
Pathways		Glycogen synthesis Myoclonic epilepsy of Lafora
Drugs
Diseases		Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
GWAS		Loneliness (multivariate analysis) ( 27629369) Mean platelet volume ( 32888494 27863252) Methadone dose in opioid dependence ( 28115739) Response to mepolizumab in severe asthma ( 29229094)
Interacting Genes		16 interacting genes: COX5A EIF2B1 EPM2AIP1 HMGXB4 NFU1 NHLRC1 PKM PPP1R3C PPP1R3D PRKAA1 PRKAA2 PRKAB2 PSMC3 SRPK2 TDG TOPORS	23 interacting genes: AGTRAP APOC1 APOC2 APOC4 CALCOCO2 CIDEB CMTM5 COIL DESI2 EPM2A FKBP7 HIRA HSPB1 MDK MORN3 NOA1 RHBDD2 SDCBP2 SH3BP4 TFIP11 TRIM23 ZNF688 ZSCAN5A
Entrez ID		7957	27247
HPRD ID		06345	12163
Ensembl ID		ENSG00000112425	ENSG00000169599
Uniprot IDs		H0UI04 O95278	Q9UMS0
PDB IDs		4R30 4RKK	2LTM 2M5O
Enriched GO Terms of Interacting Partners?
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