EPM2A and PPP1R3D

Data Source:
BioGRID (two hybrid)

		EPM2A	PPP1R3D
Description		EPM2A glucan phosphatase, laforin	protein phosphatase 1 regulatory subunit 3D
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Protein Phosphatase Type 1 Complex Glycogen Granule Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Protein Serine/threonine Phosphatase Activity Protein Binding Protein Phosphatase 1 Binding Glycogen Binding
	Biological Process	Positive Regulation Of Macroautophagy Negative Regulation Of TOR Signaling	Glycogen Metabolic Process Regulation Of Glycogen Biosynthetic Process Regulation Of Glycogen Catabolic Process Protein Dephosphorylation
Pathways		Glycogen synthesis Myoclonic epilepsy of Lafora
Drugs
Diseases		Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
GWAS		Loneliness (multivariate analysis) ( 27629369) Mean platelet volume ( 32888494 27863252) Methadone dose in opioid dependence ( 28115739) Response to mepolizumab in severe asthma ( 29229094)	Delirium ( 29631748)
Interacting Genes		16 interacting genes: COX5A EIF2B1 EPM2AIP1 HMGXB4 NFU1 NHLRC1 PKM PPP1R3C PPP1R3D PRKAA1 PRKAA2 PRKAB2 PSMC3 SRPK2 TDG TOPORS	4 interacting genes: EPM2A PPP1CA PPP1CC YWHAZ
Entrez ID		7957	5509
HPRD ID		06345	04507
Ensembl ID		ENSG00000112425	ENSG00000132825
Uniprot IDs		H0UI04 O95278	O95685 Q86X09
PDB IDs		4R30 4RKK
Enriched GO Terms of Interacting Partners?
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