NFU1 and EPM2A

		NFU1	EPM2A
Description		NFU1 iron-sulfur cluster scaffold	EPM2A glucan phosphatase, laforin
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Cytosol	Nucleus
	Molecular Function	Iron Ion Binding Protein Binding 4 Iron, 4 Sulfur Cluster Binding	Protein Binding
	Biological Process	Iron-sulfur Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer	Positive Regulation Of Macroautophagy Negative Regulation Of TOR Signaling
Pathways			Glycogen synthesis Myoclonic epilepsy of Lafora
Drugs
Diseases			Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
GWAS			Loneliness (multivariate analysis) ( 27629369) Mean platelet volume ( 32888494 27863252) Methadone dose in opioid dependence ( 28115739) Response to mepolizumab in severe asthma ( 29229094)
Interacting Genes		23 interacting genes: AGTRAP APOC1 APOC2 APOC4 CALCOCO2 CIDEB CMTM5 COIL DESI2 EPM2A FKBP7 HIRA HSPB1 MDK MORN3 NOA1 RHBDD2 SDCBP2 SH3BP4 TFIP11 TRIM23 ZNF688 ZSCAN5A	16 interacting genes: COX5A EIF2B1 EPM2AIP1 HMGXB4 NFU1 NHLRC1 PKM PPP1R3C PPP1R3D PRKAA1 PRKAA2 PRKAB2 PSMC3 SRPK2 TDG TOPORS
Entrez ID		27247	7957
HPRD ID		12163	06345
Ensembl ID		ENSG00000169599	ENSG00000112425
Uniprot IDs		Q9UMS0	H0UI04 O95278
PDB IDs		2LTM 2M5O	4R30 4RKK
Enriched GO Terms of Interacting Partners?
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