Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
BAG6 and SDC2
Data Source:
BioGRID
(two hybrid)
BAG6
SDC2
Description
BAG cochaperone 6
syndecan 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Intracellular Membrane-bounded Organelle
Extracellular Exosome
BAT3 Complex
Endoplasmic Reticulum Lumen
Golgi Lumen
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Lysosomal Lumen
Collagen-containing Extracellular Matrix
Molecular Function
Signaling Receptor Binding
Protein Binding
Polyubiquitin Modification-dependent Protein Binding
Ubiquitin Protein Ligase Binding
Ribosome Binding
Misfolded Protein Binding
Proteasome Binding
Ubiquitin-specific Protease Binding
Protein Binding
PDZ Domain Binding
Identical Protein Binding
Biological Process
Kidney Development
Immune Response-activating Cell Surface Receptor Signaling Pathway
Chromatin Organization
Ubiquitin-dependent Protein Catabolic Process
Apoptotic Process
Synaptonemal Complex Assembly
Spermatogenesis
Brain Development
Proteasomal Protein Catabolic Process
Internal Peptidyl-lysine Acetylation
Natural Killer Cell Activation
Cell Differentiation
Lung Development
Ubiquitin-dependent ERAD Pathway
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Negative Regulation Of Proteolysis
Regulation Of Embryonic Development
Protein Stabilization
Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
ER-associated Misfolded Protein Catabolic Process
Tail-anchored Membrane Protein Insertion Into ER Membrane
Positive Regulation Of ERAD Pathway
Maintenance Of Unfolded Protein Involved In ERAD Pathway
Protein Localization To Cytosolic Proteasome Complex Involved In ERAD Pathway
Retinoid Metabolic Process
Glycosaminoglycan Biosynthetic Process
Glycosaminoglycan Catabolic Process
Biological_process
Cell Migration
Post-translational Protein Modification
Cellular Protein Metabolic Process
Ephrin Receptor Signaling Pathway
Dendrite Morphogenesis
Regulation Of Dendrite Morphogenesis
Leukocyte Migration
Pathways
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
A tetrasaccharide linker sequence is required for GAG synthesis
HS-GAG biosynthesis
HS-GAG biosynthesis
HS-GAG degradation
Cell surface interactions at the vascular wall
Syndecan interactions
Syndecan interactions
Defective B4GALT7 causes EDS, progeroid type
Defective B3GAT3 causes JDSSDHD
Defective EXT2 causes exostoses 2
Defective EXT1 causes exostoses 1, TRPS2 and CHDS
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
EPHB-mediated forward signaling
Defective B3GALT6 causes EDSP2 and SEMDJL1
Post-translational protein phosphorylation
Retinoid metabolism and transport
Drugs
Sargramostim
Diseases
GWAS
Asthma (
31619474
)
Asthma (childhood onset) (
31619474
)
Asthma and major depressive disorder (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Blood protein levels (
28240269
)
Height (
28552196
)
Inflammatory bowel disease (
28067908
)
Malaria (
31844061
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Medication use (HMG CoA reductase inhibitors) (
31015401
)
Schizophrenia (
23894747
)
Small cell lung carcinoma (
28604730
)
Smoking status (ever vs never smokers) (
30643258
)
Ulcerative colitis (
28067908
)
Post-traumatic stress disorder (
26114229
)
Refractive error (
32231278
)
Interacting Genes
118 interacting genes:
ACVR1B
AMFR
AMTN
ANTKMT
ANXA7
APBB1IP
ARPC3
ATN1
ATXN2
B2M
C1QA
CD93
CDK16
CDK4
CDK5
CDKN1A
CDSN
CHN2
CILK1
CLU
CSNK2B
CSTF2
CTAG1A
CTAG1B
CTCFL
CTSB
CTSE
CTSL
CXCL8
CYSRT1
DMKN
DNAJB11
DPT
EDN1
EFEMP1
EFEMP2
ELP1
EP300
FAM9B
FAS
FKBP2
FZD4
GADD45A
GET4
GLRA2
GOLGA6L9
GSK3B
HSPA13
HSPA8
IGF2
IGFBP5
IMMT
IQCG
KLHL12
KPNA2
LBP
MAPK6
MEST
MTNR1A
MYDGF
NBL1
NCR3
NDUFA6
NDUFB11
NOMO1
NPY
NR1H2
PELP1
PIN1
PLA2G2A
PLK1
PLPP2
PLPPR3
POLR2J
PRKAR1B
PRMT2
PRNP
PRPF40A
PTH
PTN
PTPN12
RAB8A
RAC1
RCC1
RCN2
REG1B
RNF126
S100A4
SDC2
SEC61A1
SEC61B
SERPING1
SERPINH1
SERPINI2
SETDB1
SGTA
SMN1
SPP1
SRGN
STX5
TAC1
TDGF1
TENT5A
TFCP2
TK1
TOMM20
TP53
TP63
TTR
UBL4B
UBL7
UBQLN1
UBQLN2
UBQLN4
USP13
VAMP2
XRN1
ZFYVE9
28 interacting genes:
ANOS1
ASPH
BAG6
CASK
CSF2
CYP2C18
EPHB2
EZR
FGF2
FN1
HGF
ITGB4
LAMA3
NF1
PF4
PPP3CC
PRKCA
PRKCB
PRKCG
REG3A
SDCBP
SERPINA1
SERPINC1
SPARC
TGFB1
TGFBR3
TNFSF13
TRAPPC4
Entrez ID
7917
6383
HPRD ID
00808
00803
Ensembl ID
ENSG00000204463
ENSG00000169439
Uniprot IDs
A0A1U9X7A6
P46379
A0A024R9D1
E9PBI9
P34741
PDB IDs
1WX9
2N9P
4DWF
4EEW
4WWR
4X86
6AU8
6ITH
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?