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SDC2
Description
syndecan 2
Image
GO Annotations
Cellular Component
Endoplasmic Reticulum Lumen
Golgi Lumen
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Lysosomal Lumen
Collagen-containing Extracellular Matrix
Molecular Function
Protein Binding
PDZ Domain Binding
Identical Protein Binding
Biological Process
Retinoid Metabolic Process
Glycosaminoglycan Biosynthetic Process
Glycosaminoglycan Catabolic Process
Biological_process
Cell Migration
Post-translational Protein Modification
Cellular Protein Metabolic Process
Ephrin Receptor Signaling Pathway
Dendrite Morphogenesis
Regulation Of Dendrite Morphogenesis
Leukocyte Migration
Pathways
A tetrasaccharide linker sequence is required for GAG synthesis
HS-GAG biosynthesis
HS-GAG biosynthesis
HS-GAG degradation
Cell surface interactions at the vascular wall
Syndecan interactions
Syndecan interactions
Defective B4GALT7 causes EDS, progeroid type
Defective B3GAT3 causes JDSSDHD
Defective EXT2 causes exostoses 2
Defective EXT1 causes exostoses 1, TRPS2 and CHDS
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
EPHB-mediated forward signaling
Defective B3GALT6 causes EDSP2 and SEMDJL1
Post-translational protein phosphorylation
Retinoid metabolism and transport
Drugs
Sargramostim
Diseases
GWAS
Post-traumatic stress disorder (
26114229
)
Refractive error (
32231278
)
Interacting Genes
28 interacting genes:
ANOS1
ASPH
BAG6
CASK
CSF2
CYP2C18
EPHB2
EZR
FGF2
FN1
HGF
ITGB4
LAMA3
NF1
PF4
PPP3CC
PRKCA
PRKCB
PRKCG
REG3A
SDCBP
SERPINA1
SERPINC1
SPARC
TGFB1
TGFBR3
TNFSF13
TRAPPC4
Entrez ID
6383
HPRD ID
00803
Ensembl ID
ENSG00000169439
Uniprot IDs
A0A024R9D1
E9PBI9
P34741
PDB IDs
6ITH
Enriched GO Terms of Interacting Partners
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