PHF23 and PRSS23

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PHF23	PRSS23
Description		PHD finger protein 23	serine protease 23
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Endoplasmic Reticulum Lumen Extracellular Exosome
	Molecular Function	Protein Binding Metal Ion Binding	Serine-type Endopeptidase Activity Protein Binding
	Biological Process	Autophagy Positive Regulation Of Protein Ubiquitination Negative Regulation Of Autophagosome Maturation Negative Regulation Of Autophagosome Assembly	Proteolysis Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494)	Blood urea nitrogen levels ( 31152163) Chronic obstructive pulmonary disease ( 30804561) FEV1 ( 30804560) Heel bone mineral density ( 30598549 28869591) Intraocular pressure ( 29617998 29785010) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 30804560) Peak expiratory flow ( 30804560)
Interacting Genes		6 interacting genes: ERBB2 LRSAM1 PRSS23 STK11 TRIM55 TRIM63	26 interacting genes: ACTG1 APP B2M CHP1 EFNA3 FXR1 GATD1 GRK6 HSPA4 MAPK8IP2 NCAPD3 NIPBL NOC4L ODF2L PDPK1 PHF23 PPIA RACGAP1 RECQL4 RPL4P5 SEC11C SHMT1 SLC25A6 TCF12 TMEM222 TRAPPC4
Entrez ID		79142	11098
HPRD ID		08325	07149
Ensembl ID		ENSG00000040633	ENSG00000150687
Uniprot IDs		Q9BUL5	O95084
PDB IDs		6WXK
Enriched GO Terms of Interacting Partners?
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