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SEMA4A

Description semaphorin 4A
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Space
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
Molecular Function
  • Protein Binding
  • Semaphorin Receptor Binding
  • Chemorepellent Activity
Biological Process
  • Angiogenesis
  • Neural Crest Cell Migration
  • Axon Guidance
  • Regulation Of Cell Shape
  • Regulation Of Endothelial Cell Migration
  • Negative Regulation Of Angiogenesis
  • Positive Regulation Of Cell Migration
  • T-helper 1 Cell Differentiation
  • Negative Regulation Of Axon Extension Involved In Axon Guidance
  • Negative Chemotaxis
  • Semaphorin-plexin Signaling Pathway
  • Positive Regulation Of Excitatory Synapse Assembly
  • Positive Regulation Of Inhibitory Synapse Assembly
Pathways
  • Other semaphorin interactions
Drugs
Diseases
  • Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
  • Retinitis pigmentosa (RP)
GWAS
  • Ischemic stroke ( 29531354)
  • Ischemic stroke (small-vessel) ( 29531354)
  • Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
  • Platelet count ( 32888494)
  • Stroke ( 29531354)
  • Systolic blood pressure ( 30224653)
Interacting Genes 3 interacting genes: DDX54 HAVCR1 PLXND1
Entrez ID 64218
HPRD ID 09528
Ensembl ID ENSG00000196189
Uniprot IDs B4DKS5 Q9H3S1
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025