PRR14 and SH3BP4

Data Source:
BioGRID (two hybrid)

		PRR14	SH3BP4
Description		proline rich 14	SH3 domain binding protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Lamina Nucleoplasm Chromosome	Nucleus Cytoplasm Clathrin-coated Pit Clathrin-coated Vesicle Extracellular Exosome
	Molecular Function	Protein Binding	GDP-dissociation Inhibitor Activity Protein Binding Small GTPase Binding Identical Protein Binding
	Biological Process	Muscle Organ Development	Endocytosis Negative Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Negative Regulation Of Cell Growth Negative Regulation Of TOR Signaling Negative Regulation Of GTPase Activity Amino Acid Import Regulation Of Catalytic Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus
Pathways			Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Immunoglobulin light chain (AL) amyloidosis ( 28025584) Irritable mood ( 29500382) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Neurociticism ( 29500382)	Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obstetric antiphospholipid syndrome ( 28424481) Orofacial clefts ( 22419666) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		5 interacting genes: APP CBX3 CBX5 SH3BP4 SH3GL2	22 interacting genes: C2orf73 CCT3 CEP78 CIZ1 DNAJA4 FKBP4 GAPDHS GIPC1 GKAP1 HSPA5 MPHOSPH8 MRGBP NFU1 PLEKHA1 PRR14 PSMA1 TCP1 TTC1 TXNL1 YWHAE YWHAG ZBTB37
Entrez ID		78994	23677
HPRD ID		14541	09285
Ensembl ID		ENSG00000156858	ENSG00000130147
Uniprot IDs		A0A024QZB5 Q9BWN1	Q9P0V3
PDB IDs
Enriched GO Terms of Interacting Partners?
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