SH3BP4 and PRR14

Data Source:
BioGRID (two hybrid)

		SH3BP4	PRR14
Description		SH3 domain binding protein 4	proline rich 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Clathrin-coated Pit Clathrin-coated Vesicle Extracellular Exosome	Nuclear Lamina Nucleoplasm Chromosome
	Molecular Function	GDP-dissociation Inhibitor Activity Protein Binding Small GTPase Binding Identical Protein Binding	Protein Binding
	Biological Process	Endocytosis Negative Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Negative Regulation Of Cell Growth Negative Regulation Of TOR Signaling Negative Regulation Of GTPase Activity Amino Acid Import Regulation Of Catalytic Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus	Muscle Organ Development
Pathways		Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obstetric antiphospholipid syndrome ( 28424481) Orofacial clefts ( 22419666) Platelet count ( 32888494) Plateletcrit ( 32888494)	Immunoglobulin light chain (AL) amyloidosis ( 28025584) Irritable mood ( 29500382) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Neurociticism ( 29500382)
Interacting Genes		22 interacting genes: C2orf73 CCT3 CEP78 CIZ1 DNAJA4 FKBP4 GAPDHS GIPC1 GKAP1 HSPA5 MPHOSPH8 MRGBP NFU1 PLEKHA1 PRR14 PSMA1 TCP1 TTC1 TXNL1 YWHAE YWHAG ZBTB37	5 interacting genes: APP CBX3 CBX5 SH3BP4 SH3GL2
Entrez ID		23677	78994
HPRD ID		09285	14541
Ensembl ID		ENSG00000130147	ENSG00000156858
Uniprot IDs		Q9P0V3	A0A024QZB5 Q9BWN1
PDB IDs
Enriched GO Terms of Interacting Partners?
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