SH3BP4 and TXNL1

Data Source:
BioGRID (two hybrid)

		SH3BP4	TXNL1
Description		SH3 domain binding protein 4	thioredoxin like 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Clathrin-coated Pit Clathrin-coated Vesicle Extracellular Exosome	Proteasome Complex Nucleus Cytoplasm Cytosol
	Molecular Function	GDP-dissociation Inhibitor Activity Protein Binding Small GTPase Binding Identical Protein Binding	Disulfide Oxidoreductase Activity
	Biological Process	Endocytosis Negative Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Negative Regulation Of Cell Growth Negative Regulation Of TOR Signaling Negative Regulation Of GTPase Activity Amino Acid Import Regulation Of Catalytic Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus
Pathways		Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obstetric antiphospholipid syndrome ( 28424481) Orofacial clefts ( 22419666) Platelet count ( 32888494) Plateletcrit ( 32888494)	Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Chronotype ( 30696823) Diverticular disease ( 30177863) General risk tolerance (MTAG) ( 30643258) Morning person ( 30696823) Number of sexual partners ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		22 interacting genes: C2orf73 CCT3 CEP78 CIZ1 DNAJA4 FKBP4 GAPDHS GIPC1 GKAP1 HSPA5 MPHOSPH8 MRGBP NFU1 PLEKHA1 PRR14 PSMA1 TCP1 TTC1 TXNL1 YWHAE YWHAG ZBTB37	5 interacting genes: CDC42 HSPB1 PSMC3 SH3BP4 SUMO4
Entrez ID		23677	9352
HPRD ID		09285	04335
Ensembl ID		ENSG00000130147	ENSG00000091164
Uniprot IDs		Q9P0V3	O43396 V9HW51
PDB IDs			1GH2 1WWY
Enriched GO Terms of Interacting Partners?
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