SH3BP4 and NFU1

Data Source:
BioGRID (two hybrid)

		SH3BP4	NFU1
Description		SH3 domain binding protein 4	NFU1 iron-sulfur cluster scaffold
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Clathrin-coated Pit Clathrin-coated Vesicle Extracellular Exosome	Nucleus Nucleoplasm Mitochondrion Cytosol
	Molecular Function	GDP-dissociation Inhibitor Activity Protein Binding Small GTPase Binding Identical Protein Binding	Iron Ion Binding Protein Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Endocytosis Negative Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Negative Regulation Of Cell Growth Negative Regulation Of TOR Signaling Negative Regulation Of GTPase Activity Amino Acid Import Regulation Of Catalytic Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus	Iron-sulfur Cluster Assembly Protein Maturation By Iron-sulfur Cluster Transfer
Pathways		Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obstetric antiphospholipid syndrome ( 28424481) Orofacial clefts ( 22419666) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		22 interacting genes: C2orf73 CCT3 CEP78 CIZ1 DNAJA4 FKBP4 GAPDHS GIPC1 GKAP1 HSPA5 MPHOSPH8 MRGBP NFU1 PLEKHA1 PRR14 PSMA1 TCP1 TTC1 TXNL1 YWHAE YWHAG ZBTB37	23 interacting genes: AGTRAP APOC1 APOC2 APOC4 CALCOCO2 CIDEB CMTM5 COIL DESI2 EPM2A FKBP7 HIRA HSPB1 MDK MORN3 NOA1 RHBDD2 SDCBP2 SH3BP4 TFIP11 TRIM23 ZNF688 ZSCAN5A
Entrez ID		23677	27247
HPRD ID		09285	12163
Ensembl ID		ENSG00000130147	ENSG00000169599
Uniprot IDs		Q9P0V3	Q9UMS0
PDB IDs			2LTM 2M5O
Enriched GO Terms of Interacting Partners?
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