SH3BP4 and GAPDHS

Data Source:
BioGRID (two hybrid)

		SH3BP4	GAPDHS
Description		SH3 domain binding protein 4	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Clathrin-coated Pit Clathrin-coated Vesicle Extracellular Exosome	Nucleus Cytosol
	Molecular Function	GDP-dissociation Inhibitor Activity Protein Binding Small GTPase Binding Identical Protein Binding	Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity Protein Binding NADP Binding NAD Binding
	Biological Process	Endocytosis Negative Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Negative Regulation Of Cell Growth Negative Regulation Of TOR Signaling Negative Regulation Of GTPase Activity Amino Acid Import Regulation Of Catalytic Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus	Gluconeogenesis Glycolytic Process Flagellated Sperm Motility Positive Regulation Of Glycolytic Process Canonical Glycolysis
Pathways		Amino acids regulate mTORC1	Association of TriC/CCT with target proteins during biosynthesis Glycolysis Gluconeogenesis
Drugs			NADH Zinc (+)-Rutamarin alcohol N-naphthalen-1-ylmethyl-2'-[3,5-dimethoxybenzamido]-2'-deoxy-adenosine 2'-Deoxy-2'-[(3,5-dimethoxybenzoyl)amino]-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]adenosine Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obstetric antiphospholipid syndrome ( 28424481) Orofacial clefts ( 22419666) Platelet count ( 32888494) Plateletcrit ( 32888494)	Diastolic blood pressure ( 28234671) Platelet count ( 32888494) Plateletcrit ( 32888494) Systolic blood pressure ( 28234671)
Interacting Genes		22 interacting genes: C2orf73 CCT3 CEP78 CIZ1 DNAJA4 FKBP4 GAPDHS GIPC1 GKAP1 HSPA5 MPHOSPH8 MRGBP NFU1 PLEKHA1 PRR14 PSMA1 TCP1 TTC1 TXNL1 YWHAE YWHAG ZBTB37	3 interacting genes: APP SH3BP4 ZMYND19
Entrez ID		23677	26330
HPRD ID		09285	13566
Ensembl ID		ENSG00000130147	ENSG00000105679
Uniprot IDs		Q9P0V3	A0A0K0K1K1 O14556
PDB IDs			3H9E 3PFW 5C7L 5C7O
Enriched GO Terms of Interacting Partners?
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