BRPF1 and USP20

Data Source:
BioGRID (two hybrid)

		BRPF1	USP20
Description		bromodomain and PHD finger containing 1	ubiquitin specific peptidase 20
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GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Plasma Membrane MOZ/MORF Histone Acetyltransferase Complex	Cytoplasm Centrosome Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Protein Binding Acetyltransferase Activator Activity Histone Binding Histone Acetyltransferase Activity (H3-K23 Specific) Metal Ion Binding	G Protein-coupled Receptor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding
	Biological Process	Histone H3 Acetylation Histone H3-K23 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Transcription, DNA-templated Regulation Of Catalytic Activity Regulation Of Signal Transduction By P53 Class Mediator	Ubiquitin-dependent Protein Catabolic Process Endocytosis Regulation Of G Protein-coupled Receptor Signaling Pathway Protein Deubiquitination Protein Phosphopantetheinylation Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination
Pathways		HATs acetylate histones Regulation of TP53 Activity through Acetylation	Ub-specific processing proteases
Drugs
Diseases
GWAS			Metabolite levels ( 23823483)
Interacting Genes		11 interacting genes: CDCA7L CEP63 CEP70 GTF2H1 H3C14 ING5 KIAA0753 NECAB1 PBXIP1 USHBP1 USP20	69 interacting genes: AGR2 ALAS1 APBA2 ARID5A ASCL1 ATP6V1G2 BEND5 BEND7 BHLHB9 BRPF1 C1QTNF2 CCNL2 CDK2AP1 CLSPN CTAG1A CTAG1B DIO2 ENKD1 EPAS1 FATE1 FTO GPRASP2 GTF2IRD1 HAND2 HIF1A HSF2BP IHO1 IRAK1BP1 ITGB3BP KLHL20 LMNA MAGEA11 MAPK6 MBD3L1 MCCD1 MDFI MEOX2 MRPL28 PBX4 PJA1 PLA2G2A PRKACA PRKCI RAD17 RSPO4 SAMD12 SPRY2 SRGAP2B STING1 TNNI1 TRIB3 TRIM23 TTC19 TTC23L ULK1 USP15 USP21 USP28 VAPA VAPB VAX1 VHL WASHC1 ZBTB10 ZFYVE26 ZNF343 ZNF408 ZNF620 ZXDB
Entrez ID		7862	10868
HPRD ID		03875	07505
Ensembl ID		ENSG00000156983	ENSG00000136878
Uniprot IDs		P55201	Q9Y2K6
PDB IDs		2D9E 2RS9 2X35 2X4W 2X4X 2X4Y 3L42 3MO8 4LC2 4QYD 4QYL 4UYE 5C6S 5C7N 5C85 5C87 5C89 5D7X 5DY7 5DYA 5DYC 5E3D 5E3G 5EM3 5EPR 5EPS 5EQ1 5ERC 5ETB 5ETD 5EV9 5EVA 5EWC 5EWD 5EWH 5EWV 5EWW 5FFV 5FFW 5FFY 5FG4 5FG5 5G4R 5G4S 5MWG 5MWH 5MWZ 5MYG 5O4S 5O4T 5O55 5O5A 5O5F 5O5H 5OV8 5OWA 5OWB 5OWE 5T4U 5T4V 6EKQ 6U04 7C4I	6KCZ
Enriched GO Terms of Interacting Partners?
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