BRPF1 and CDCA7L

Data Source:
BioGRID (two hybrid)

		BRPF1	CDCA7L
Description		bromodomain and PHD finger containing 1	cell division cycle associated 7 like
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GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Plasma Membrane MOZ/MORF Histone Acetyltransferase Complex	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	DNA Binding Protein Binding Acetyltransferase Activator Activity Histone Binding Histone Acetyltransferase Activity (H3-K23 Specific) Metal Ion Binding	Protein Binding
	Biological Process	Histone H3 Acetylation Histone H3-K23 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Transcription, DNA-templated Regulation Of Catalytic Activity Regulation Of Signal Transduction By P53 Class Mediator	Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Population Proliferation
Pathways		HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS			Breast cancer ( 29059683) Height ( 20189936) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Pre-treatment viral load in HIV-1 infection ( 31219150) Squamous cell lung carcinoma ( 28604730) Urate levels in obese individuals ( 25811787)
Interacting Genes		11 interacting genes: CDCA7L CEP63 CEP70 GTF2H1 H3C14 ING5 KIAA0753 NECAB1 PBXIP1 USHBP1 USP20	68 interacting genes: ABT1 ANKRD1 ANKRD11 ANKRD23 AVPI1 AXIN1 BAG5 BEND7 BHLHB9 BRPF1 BYSL CARD9 CAVIN1 CCDC116 CCDC33 CEP70 CTNNBL1 DAXX DEDD2 DMAP1 EIF4A3 FAM217B FAM9B GOLGA2 HSF2BP ING5 JADE2 KRTAP10-7 LMO1 MCRS1 MDFI MEOX2 MFAP1 MLH1 MORN3 MRPL28 MYC NDUFB7 NOL12 NOP2 PBX1 PBX2 PICK1 PIH1D1 PIP4K2B PPP1R16A PPP1R16B PRDM14 PRPF31 RRP7A SNRNP48 SSX1 SSX2IP STX11 SUV39H1 TADA2A TFPT TNNI1 TRAF3IP3 TRIM42 UBL4A UTP3 VDR ZGPAT ZNF250 ZNF438 ZNF620 ZNF821
Entrez ID		7862	55536
HPRD ID		03875	11481
Ensembl ID		ENSG00000156983	ENSG00000164649
Uniprot IDs		P55201	A0A024RA51 A8K8X5 Q96GN5
PDB IDs		2D9E 2RS9 2X35 2X4W 2X4X 2X4Y 3L42 3MO8 4LC2 4QYD 4QYL 4UYE 5C6S 5C7N 5C85 5C87 5C89 5D7X 5DY7 5DYA 5DYC 5E3D 5E3G 5EM3 5EPR 5EPS 5EQ1 5ERC 5ETB 5ETD 5EV9 5EVA 5EWC 5EWD 5EWH 5EWV 5EWW 5FFV 5FFW 5FFY 5FG4 5FG5 5G4R 5G4S 5MWG 5MWH 5MWZ 5MYG 5O4S 5O4T 5O55 5O5A 5O5F 5O5H 5OV8 5OWA 5OWB 5OWE 5T4U 5T4V 6EKQ 6U04 7C4I	5YI9 6EMO
Enriched GO Terms of Interacting Partners?
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