MOGS and CHGB

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MOGS	CHGB
Description		mannosyl-oligosaccharide glucosidase	chromogranin B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Exosome	Extracellular Space Endoplasmic Reticulum Lumen Secretory Granule
	Molecular Function	Mannosyl-oligosaccharide Glucosidase Activity Glucosidase Activity	Hormone Activity Protein Binding
	Biological Process	Protein Folding Protein N-linked Glycosylation Oligosaccharide Metabolic Process	Signal Transduction Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Defective MOGS causes MOGS-CDG (CDG-2b) N-glycan trimming in the ER and Calnexin/Calreticulin cycle Maturation of spike protein Maturation of spike protein	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases		Congenital disorders of glycosylation (CDG) type II
GWAS			Metabolite levels ( 23823483) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		1 interacting genes: CHGB	34 interacting genes: ACACA ANXA7 APP ATXN2 CBFB CCDC92 CDKN1A FGFR3 LRRK1 LRRK2 MARK3 MFHAS1 MGLL MOGS OGG1 PKN2 POLD1 POLR2E PRAG1 PTEN RAC2 RAP1B RCC1 RXRG S100A8 SAFB2 SLC25A6 TAZ TK1 TUBB2A TWF2 UBQLN1 UBTF YLPM1
Entrez ID		7841	1114
HPRD ID		03214	07512
Ensembl ID		ENSG00000115275	ENSG00000089199
Uniprot IDs		A0A384MDR6 Q13724 Q58F09	P05060
PDB IDs
Enriched GO Terms of Interacting Partners?
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