SLC30A4 and PEDS1-UBE2V1

Data Source:
BioGRID (two hybrid)

		SLC30A4	PEDS1-UBE2V1
Description		solute carrier family 30 member 4	PEDS1-UBE2V1 readthrough
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Late Endosome Plasma Membrane Integral Component Of Membrane Late Endosome Membrane
	Molecular Function	Zinc Ion Transmembrane Transporter Activity Protein Binding
	Biological Process	Response To Toxic Substance Response To Zinc Ion Zinc Ion Homeostasis Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport
Pathways			NOD1/2 Signaling Pathway TICAM1, RIP1-mediated IKK complex recruitment Downstream TCR signaling FCERI mediated NF-kB activation TAK1 activates NFkB by phosphorylation and activation of IKKs complex activated TAK1 mediates p38 MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 CLEC7A (Dectin-1) signaling Interleukin-1 signaling IRAK1 recruits IKK complex IKK complex recruitment mediated by RIP1 Aggrephagy Aggrephagy TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Response to fenofibrate (adiponectin levels) ( 23149075)
Interacting Genes		14 interacting genes: BTN2A2 CLN6 CMTM5 FZD7 IER3IP1 LEPROTL1 NSG1 PEDS1-UBE2V1 SERP2 TMEM100 TMEM60 TNF TNFRSF10C YIPF6	17 interacting genes: AQP6 CNR2 CREB3L1 FAM209A GPR152 PGRMC2 SLC10A1 SLC10A6 SLC18A3 SLC30A4 STOM TMEM31 TMEM52B TMX2 TRAF6 TRHR UBE2N
Entrez ID		7782	387522
HPRD ID		03651	11926
Ensembl ID		ENSG00000104154	ENSG00000124208
Uniprot IDs		O14863	A5PLL7 Q13404
PDB IDs			2A4D 2C2V 2HLW 6D6I
Enriched GO Terms of Interacting Partners?
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